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Estimating the Effect of Preventable Treatment Discontinuation on Health Outcomes.

Author: BradburyB D, BrookhartM A, DluzniewskiP J, KshirsagarA, ReamsD, WalshL

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study estimated the effect of potentially preventable discontinuation of cinacalcet, a medication used to treat secondary hyperparathyroidism, on mortality and heart failure in patients with end-stage renal disease. The study found that potentially preventable discontinuation was associated with a 2.9% increase in mortality at 1 year and a 4.6% increase in mortality at 2 years. The association between cinacalcet persistence and heart failure hospitalization risk was sensitive to the outcome definition.
Paper Details　
Original Abstract of the Article :
BACKGROUND: There is increased interest in studying the effects of medication adherence on health outcomes. However, if patients appropriately stop treatment because of side effects and treatment failure, it is neither possible nor clinically meaningful to estimate the effect of full medication adhe...See full text at original site
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引用元：
https://doi.org/10.1097/EDE.0000000000000766

データ提供：米国国立医学図書館（NLM）

The Impact of Preventable Treatment Discontinuation on Health Outcomes

In the desert of healthcare, it's vital to understand the impact of treatment adherence on patient outcomes. This research focuses on the effects of preventable discontinuation of cinacalcet, a medication used to treat secondary hyperparathyroidism in patients with end-stage renal disease. The authors developed a unique method to estimate the impact of preventable treatment discontinuation, accounting for patients who might have stopped treatment for legitimate medical reasons. Their findings suggest that preventable discontinuation of cinacalcet is associated with a significant increase in mortality and heart failure risk. The research emphasizes the importance of adherence to treatment plans to improve patient outcomes.

Preventable Treatment Discontinuation: A Hidden Danger

The study highlights the significant impact of preventable treatment discontinuation on patient outcomes. The increased mortality and heart failure risk associated with stopping treatment underscore the importance of ensuring adherence to prescribed medication regimes.

The Importance of Patient Education and Support

The findings highlight the need for effective patient education and support systems to promote treatment adherence. This can involve clear communication about the benefits and risks of medications, addressing concerns about side effects, and providing resources to help patients manage their conditions.

Dr.Camel's Conclusion

The desert of healthcare is filled with challenges, and treatment adherence is a key factor in navigating this terrain. This research emphasizes the importance of preventing unnecessary treatment discontinuation and highlights the need for patient education and support systems to ensure optimal health outcomes.

Date :
  1. Date Completed 2018-07-24
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28991002

DOI: Digital Object Identifier

10.1097/EDE.0000000000000766

Related Literature

Article Analysis
・Side Effects of cinacalcet
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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