Potential drug-drug interactions of OMBITASVIR, PARITAPREVIR/ritonavir ± DASABUVIR ± ribavirin in clinical practice.

Author: ArdèvolMercè, CarriónJose A, GallegoAdolfo, González-ColominasElena, LensSabela, LondoñoMaría-Carlota, LópezDulce, MariñoZoe, MojalSergi, MorillasRosa M, PagèsNeus, SolàRicard, TorrasXavier

Paper Details 
Original Abstract of the Article :
Drug-drug interactions (DDIs) with ombitasvir/paritaprevir/ritonavir with or without dasabuvir and with or without ribavirin (OBV/PTV/r ± DSV ± RBV) are common in clinical trials. Our aim was to analyze the prevalence and management of potential DDIs and adverse events (AEs) related to DDIs in patie...See full text at original site
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引用元:
https://doi.org/10.1111/jgh.14014

データ提供:米国国立医学図書館(NLM)

Navigating Drug Interactions: A Deep Dive into Hepatitis C Treatment

The treatment of chronic hepatitis C (CHC) is a complex endeavor, often involving multiple medications that can interact in unexpected ways. This study, like a meticulous desert explorer mapping a complex terrain, analyzes the prevalence and management of potential drug-drug interactions (DDIs) in patients receiving a specific hepatitis C treatment regimen.

The authors, like wise desert guides, focus on the interactions associated with the ombitasvir/paritaprevir/ritonavir combination, with or without dasabuvir and ribavirin. Their findings highlight the challenges and intricacies of managing DDIs in clinical practice.

DDIs: A Common Challenge in Hepatitis C Treatment

This study, like a mirror reflecting the realities of CHC treatment, reveals that DDIs are a frequent occurrence. The authors emphasize the importance of careful monitoring and management of these interactions to optimize treatment outcomes and minimize adverse events. This research sheds light on the complex interplay between medications, reminding us that a thorough understanding of DDIs is crucial for safe and effective treatment.

Optimizing Hepatitis C Treatment: A Collaborative Approach

The authors emphasize the importance of collaboration between healthcare providers and patients in navigating DDIs. This collaborative approach, like a caravan in the desert, ensures that treatment is tailored to the individual patient's needs and potential risks are minimized. Open communication and a comprehensive understanding of DDIs are essential for ensuring optimal treatment outcomes.

Dr. Camel's Conclusion

The desert of hepatitis C treatment can be challenging, but with careful navigation, patients can achieve successful outcomes. This study underscores the importance of understanding and managing potential drug interactions. It's a reminder that collaboration between healthcare providers and patients, like a caravan united in its journey, is key to a smooth and successful trek through the treatment landscape.

Date :
  1. Date Completed 2018-08-10
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

28994141

DOI: Digital Object Identifier

10.1111/jgh.14014

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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