Raloxifene reduces the risk of local alveolar bone destruction in a mouse model of periodontitis combined with systemic postmenopausal osteoporosis.

Author: HirataMichiko, IchimaruRyota, InadaMasaki, MatsumotoChiho, MiyauraChisato, MurphyGillian, NagaseHideaki, NumabeYukihiro, TominariTsukasa, WatanabeKenta, YoshinouchiShosei

Paper Details 
Original Abstract of the Article :
Periodontitis is characterized by local inflammation leading to tooth loss and severe destruction of alveolar bone. Raloxifene is a selective estrogen receptor modulator (SERM) that halts estrogen deficiency-induced systemic bone loss in postmenopausal osteoporosis without the side effects of cancer...See full text at original site
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引用元:
https://doi.org/10.1016/j.archoralbio.2017.09.017

データ提供:米国国立医学図書館(NLM)

Raloxifene reduces the risk of local alveolar bone destruction

This research delves into the world of bone health, particularly focusing on the effects of raloxifene, a medication used to treat osteoporosis, on alveolar bone loss in periodontitis. It's like exploring a vast desert landscape, where the health of the surrounding ecosystem is interconnected with the well-being of individual plants. The study investigates the potential of raloxifene to prevent alveolar bone loss in a mouse model of periodontitis and osteoporosis.

A Potential Treatment for Bone Loss

The study provides evidence that raloxifene may have beneficial effects on alveolar bone loss in the context of periodontitis and osteoporosis. This finding suggests that raloxifene could be a potential therapeutic option for patients suffering from these conditions, potentially improving bone health and reducing the risk of tooth loss.

Maintaining Bone Health

This research emphasizes the importance of maintaining bone health, particularly for individuals at risk of osteoporosis and periodontitis. This includes maintaining a healthy diet rich in calcium and vitamin D, engaging in regular weight-bearing exercise, and consulting with a healthcare professional for appropriate treatment and prevention strategies. By taking these proactive steps, we can help preserve our bone health and prevent the debilitating effects of bone loss.

Dr. Camel's Conclusion

This study reminds us that maintaining bone health is a journey through a vast and complex desert, where the health of our bones is interconnected with various aspects of our overall well-being. It's a reminder that we must be vigilant in protecting our bones, particularly as we age and face an increased risk of osteoporosis and periodontitis. The findings of this study offer a glimmer of hope for a future where we can more effectively treat and prevent bone loss, ensuring that we can navigate the challenges of aging with strong and healthy bones.

Date :
  1. Date Completed 2018-08-15
  2. Date Revised 2018-08-15
Further Info :

Pubmed ID

29035723

DOI: Digital Object Identifier

10.1016/j.archoralbio.2017.09.017

Related Literature

SNS
PICO Info
in preparation
Languages

English

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