Effect of statins and non-statin LDL-lowering medications on cardiovascular outcomes in secondary prevention: a meta-analysis of randomized trials.

Author: KoskinasKonstantinos C, MachFrançois, MavridisDimitris, PiccoloRaffaele, RäberLorenz, SiontisGeorge C M, WindeckerStephan

Paper Details 
Original Abstract of the Article :
Current evidence on dyslipidaemia management has expanded to novel treatments and very low achieved levels of low-density lipoprotein cholesterol (LDL-C). We sought to compare the clinical impact of more-intensive vs. less-intensive LDL-C lowering by means of statins and currently recommended non-st...See full text at original site
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引用元:
https://doi.org/10.1093/eurheartj/ehx566

データ提供:米国国立医学図書館(NLM)

Statins and Non-Statin Medications: A Comprehensive Review

The management of dyslipidemia, a condition characterized by abnormal lipid levels, is an ongoing area of research and clinical practice. This study delves into the efficacy of statins and non-statin medications in secondary prevention of cardiovascular events. The authors conducted a meta-analysis of randomized trials, comparing the impact of intensive versus less-intensive LDL-C lowering on cardiovascular outcomes. Their findings provide a comprehensive overview of the current evidence on the role of statins and non-statins in secondary prevention.

Balancing LDL-C Reduction with Cardiovascular Risk

This study provides valuable insights into the complex interplay between LDL-C lowering and cardiovascular risk. The researchers found that both statins and non-statin medications effectively reduce LDL-C levels. However, they emphasize the need for individualized treatment approaches, considering the specific needs and risks of each patient.

A Comprehensive Approach to Dyslipidemia Management

This study underscores the importance of a multifaceted approach to dyslipidemia management. The researchers highlight the need to consider both statins and non-statin medications, as well as lifestyle modifications, in developing effective treatment strategies. Their findings emphasize the crucial role of personalized medicine in optimizing cardiovascular health.

Dr.Camel's Conclusion

The field of cardiovascular disease management, like a vast desert landscape, is constantly evolving. This study offers a comprehensive overview of the current evidence on statins and non-statins, providing valuable insights for healthcare professionals and patients. The researchers' findings highlight the importance of evidence-based medicine and personalized treatment approaches in optimizing cardiovascular health.

Date :
  1. Date Completed 2019-11-13
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

29069377

DOI: Digital Object Identifier

10.1093/eurheartj/ehx566

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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