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Mefloquine for preventing malaria during travel to endemic areas.

Author: MaayanNicola, PaceCheryl, SaundersRachel, SinclairDavid, Tickell-PainterMaya

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Mefloquine is a highly effective antimalarial agent, but it may be associated with psychological side effects, particularly abnormal dreams, anxiety, insomnia, and depressed mood. The absolute risk of malaria during short-term travel appears low with all three established antimalarial agents (mefloquine, doxycycline, and atovaquone-proguanil). The choice of antimalarial agent depends on individual traveller's preference.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Mefloquine is one of four antimalarial agents commonly recommended for preventing malaria in travellers to malaria-endemic areas. Despite its high efficacy, there is controversy about its psychological side effects. OBJECTIVES: To summarize the efficacy and safety of mefloquine used as ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686653/

データ提供：米国国立医学図書館（NLM）

Mefloquine: A Powerful Tool in the Fight Against Malaria, but with a Few Caveats

Dr. Camel here, guiding you through the world of travel medicine! This comprehensive review, like a seasoned explorer charting the vast landscape of malaria prevention, examines the efficacy and safety of Mefloquine, a commonly prescribed antimalarial medication, for preventing malaria in travelers to endemic areas. Mefloquine, like a potent antidote against the harsh realities of malaria, has proven highly effective in preventing the disease. However, as with any powerful tool, it's important to understand its potential side effects, particularly the controversial issue of psychological side effects.

The authors, like skilled navigators in the treacherous desert of malaria prevention, conducted a thorough analysis of existing research, revealing that while Mefloquine is highly effective in preventing malaria, it may be associated with an increased risk of adverse effects, including abnormal dreams, insomnia, anxiety, and depressed mood. They also found that Mefloquine was more likely to be discontinued due to adverse effects compared to alternative antimalarial medications like Atovaquone-Proguanil.

Navigating the Risks and Benefits of Mefloquine: A Guide for Travelers

This review provides valuable insights for travelers seeking to protect themselves from malaria. While Mefloquine offers strong protection against the disease, it's essential to weigh its potential benefits against its potential side effects. Open communication with your doctor is key to making an informed decision about the most appropriate antimalarial medication for your individual needs and travel itinerary.

The Desert of Travel Medicine: A Journey of Preparation and Prudence

Traveling to malaria-endemic areas, like venturing into a vast and often unpredictable desert, requires careful planning and preparation. Understanding the risks and benefits of different antimalarial medications is crucial to ensuring a safe and enjoyable journey. Always consult with your doctor to discuss the most suitable antimalarial medication for your specific needs and travel plans.

Dr. Camel's Conclusion

This review, like a compass guiding travelers through the treacherous desert of malaria, highlights the importance of informed decision-making when choosing an antimalarial medication. It underscores the importance of weighing the potential benefits against the risks, ensuring the safest and most effective protection against this potentially life-threatening disease. As Dr. Camel, I encourage travelers to prioritize their health and safety, making informed choices that align with their individual needs and travel destinations.

Date :
  1. Date Completed 2018-09-28
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

29083100

DOI: Digital Object Identifier

PMC5686653

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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