Effects of High- and Low-Fat Meals on the Pharmacokinetics of Ozanimod, a Novel Sphingosine-1-Phosphate Receptor Modulator.

Author: FrohnaPaul A, HartungJeffrey P, TompkinsCindy-Ann, TranJonathan Q

Paper Details 
Original Abstract of the Article :
Ozanimod (RPC1063) is an oral selective modulator of the sphingosine-1-phosphate 1 and 5 receptors under development for the treatment of relapsing multiple sclerosis and inflammatory bowel disease. The effects of high-fat and low-fat meals on the pharmacokinetics (PK) of a single oral dose of ozani...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099448/

データ提供:米国国立医学図書館(NLM)

Ozanimod: A New Drug for Multiple Sclerosis and Inflammatory Bowel Disease

The search for new and effective treatments for chronic diseases like multiple sclerosis (MS) and inflammatory bowel disease (IBD) is a continuous endeavor. This study investigates the pharmacokinetics (PK) of ozanimod, a novel drug that modulates sphingosine-1-phosphate receptors, in healthy volunteers. The researchers assessed the impact of different meal conditions, including fasted, high-fat, and low-fat, on the absorption and distribution of ozanimod in the body. The results showed that the PK of ozanimod was not significantly affected by meal conditions, suggesting that ozanimod can be taken with or without food.

Ozanimod: A Convenient Option for Patients

This study's findings suggest that ozanimod offers a convenient treatment option for patients with MS and IBD. The researchers found that the absorption and distribution of ozanimod were not significantly impacted by meal conditions, meaning that patients can take this medication without worrying about food restrictions or timing.

New Hope for MS and IBD Patients

This study provides promising insights into the potential of ozanimod as a new treatment for MS and IBD. The researchers' findings regarding the PK of ozanimod suggest that this drug could offer an effective and convenient option for patients.

Dr.Camel's Conclusion

Ozanimod's ease of administration, like a desert oasis welcoming travelers without restrictions, makes it a promising new treatment option for MS and IBD patients. This study highlights the importance of exploring new therapies that can improve the lives of patients with chronic conditions.

Date :
  1. Date Completed 2019-10-21
  2. Date Revised 2019-10-22
Further Info :

Pubmed ID

29125718

DOI: Digital Object Identifier

PMC6099448

Related Literature

SNS
PICO Info
in preparation
Languages

English

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