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An update on prucalopride in the treatment of chronic constipation.

Author: OmerAnam, QuigleyEamonn M M

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Chronic constipation (CC) is a common gastrointestinal disorder that significantly impacts quality of life. This study reviewed the development of novel pharmacological approaches for treating CC, focusing on prucalopride, a highly selective serotonergic receptor agonist. Multiple clinical trials have demonstrated prucalopride's superiority over placebo in relieving constipation symptoms in both men and women across a broad spectrum of ages, ethnicities, and geographic locations. Prucalopride has a favorable safety profile and no signals suggest arrythmogenicity.
Paper Details　
Original Abstract of the Article :
Chronic constipation (CC) is a highly prevalent and often under-appreciated gastrointestinal disorder associated with significant impairment in quality of life. Symptoms of constipation are typically present for a number of years prior to a patient seeking help. Lifestyle modifications followed by, ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673021/

データ提供：米国国立医学図書館（NLM）

An Update on Prucalopride for Chronic Constipation

This research explores the common and often frustrating condition of chronic constipation, a challenge that affects many like a persistent sand dune blocking their path to comfort. The study examines the role of prucalopride, a medication used to stimulate gut motility, in treating chronic constipation. Think of prucalopride as a skillful desert guide, helping to clear the path for smooth and efficient travel through the digestive system.

The Efficacy of Prucalopride in Treating Chronic Constipation

This research evaluates the effectiveness of prucalopride in treating chronic constipation. It's like observing how a guide helps a caravan navigate a challenging desert terrain. The study found that prucalopride was effective in relieving symptoms of chronic constipation, offering a valuable tool for managing this common condition.

Finding Relief from Chronic Constipation

This research offers hope for individuals struggling with chronic constipation. It's like discovering a reliable source of water in the desert, providing a much-needed respite from a persistent discomfort. The study suggests that prucalopride can play a significant role in alleviating symptoms and improving quality of life for those affected by chronic constipation.

Dr. Camel's Conclusion

This research provides valuable insights into the potential of prucalopride for treating chronic constipation, offering a glimmer of hope for those seeking relief from this persistent discomfort.
Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

29147138

DOI: Digital Object Identifier

PMC5673021

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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