Paper Details

  1. Home
  2. Paper Details

Systemic and local effects of vaginal dehydroepiandrosterone (DHEA): NCCTG N10C1 (Alliance).

Author: AthertonPamela J, BartonDebra L, BirrellStephen N, DockterTravis, GriffinPatricia, LafkyJacqueline M, LoprinziCharles L, MattarBassam, ShusterLynne T, SoodRicha, TerstriepShelby A, ThielenJacqueline

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study evaluated the impact of vaginal DHEA on hormone concentrations, bone turnover, and vaginal cytology in postmenopausal women with a cancer history. Vaginal DHEA resulted in increased hormone concentrations, though still in the lowest half or quartile of the postmenopausal range, and provided more favorable effects on vaginal cytology, compared to a plain moisturizer. Estrogen concentrations in women on aromatase inhibitors were not changed.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Dehydroepiandrosterone (DHEA) is helpful for treating vaginal symptoms. This secondary analysis evaluated the impact of vaginal DHEA on hormone concentrations, bone turnover, and vaginal cytology in women with a cancer history. METHODS: Postmenopausal women, diagnosed with breast or gyn...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/29164377

データ提供：米国国立医学図書館（NLM）

DHEA: A Journey Through the Vaginal Landscape

This research explores the effects of vaginal dehydroepiandrosterone (DHEA), a hormone that can help alleviate vaginal symptoms. It's like a journey through a desert landscape, where DHEA acts as a gentle guide, restoring balance and comfort. The researchers examined the impact of vaginal DHEA on hormone levels, bone health, and vaginal cytology in women with a history of cancer. They found that DHEA effectively increased hormone levels, providing relief from vaginal symptoms and improving vaginal cell health. These findings suggest that DHEA may offer a valuable treatment option for women experiencing vaginal discomfort, particularly those with a cancer history.

DHEA's Promise for Vaginal Health

The study demonstrates the positive effects of vaginal DHEA on hormone levels and vaginal cytology. This suggests that DHEA could be a beneficial treatment for women experiencing vaginal discomfort, particularly those with a cancer history. The study also highlights the need for further research to understand the long-term implications of DHEA use in this population.

A New Frontier in Vaginal Care

This study opens up a new avenue for managing vaginal discomfort, particularly for women with a cancer history. It's important to discuss your concerns with your doctor to determine if vaginal DHEA is a suitable treatment option for you.

Dr.Camel's Conclusion

This research provides valuable insight into the potential of DHEA for improving vaginal health and wellbeing. It's like discovering a hidden oasis in a vast desert, offering hope and relief for women seeking a solution to their vaginal symptoms. The study is a reminder that research is an ongoing journey, and further exploration is needed to fully understand the benefits and potential risks of DHEA in the context of cancer and overall health.

Date :
  1. Date Completed 2019-03-11
  2. Date Revised 2019-04-02
Further Info :

Pubmed ID

29164377

DOI: Digital Object Identifier

NIHMS922299

Related Literature

Article Analysis
・Effects of prasterone vaginal
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.