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Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants: a multicentre, parallel group randomised controlled trial.
Author: AndrewsNick J, BurbidgePolly, GoldblattDavid, MillerElizabeth, PartingtonJo, PlestedEmma, RichardsonHayley, RoalfeLucy, SnapeMatthew D, SouthernJo, ThalasselisVasilli, Valente PintoMarta
Original Abstract of the Article :
Infants in the UK were first offered a pneumococcal conjugate vaccine (PCV7) in 2006, given at 2 and 4 months of age and a booster dose at 13 months (2 + 1 schedule). A 13-valent vaccine (PCV13) replaced PCV7 in 2010. We aimed to compare the post-booster antibody response in UK infants given a reduc...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805912/
データ提供:米国国立医学図書館(NLM)
Pneumococcal Vaccine: A Camel's Take on Immunization
In the world of pediatric medicine, pneumococcal conjugate vaccines (PCVs) are a cornerstone of prevention. This study delves into the effectiveness of different PCV13 immunization schedules in UK infants. The authors sought to compare the antibody response in infants who received one primary dose followed by a booster (1+1 schedule) versus the traditional two primary doses followed by a booster (2+1 schedule). This study aimed to assess the impact of these different schedules on population protection, seeking to optimize the effectiveness of this crucial vaccine.
Reduced Priming Schedule: A Potential Shift in Immunization Strategies?
The findings of this study suggest that the 1+1 schedule for PCV13 in UK infants might offer comparable antibody responses to the traditional 2+1 schedule. This potentially offers a more efficient and cost-effective immunization strategy, without compromising on the protection provided by the vaccine. However, it's crucial to consider the potential implications for population protection before implementing this strategy. Further research is needed to fully understand the long-term impact of this reduced priming schedule.
Vaccinations: A Crucial Step in Protecting Our Herd
This research underlines the importance of immunization for protecting our population. Vaccinations act as a collective shield, safeguarding us from potentially devastating diseases. As we navigate the ever-evolving landscape of infectious diseases, understanding the effectiveness of different vaccine schedules is crucial. This study provides valuable insights into the potential for optimizing immunization strategies, ensuring we continue to build a stronger and healthier herd immunity.
Dr.Camel's Conclusion
The quest for optimal immunization strategies is a constant journey, like a camel traversing a vast desert. This study offers a valuable insight into the potential of a reduced priming schedule for PCV13. While further research is needed to fully understand the implications of this approach, it represents a potential shift in immunization strategies. The results offer hope for a more efficient and effective approach to protecting our population from preventable diseases.
Date :
- Date Completed 2019-01-21
- Date Revised 2022-04-09
Further Info :
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