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Protective Effects of Antimuscarinics on the Bladder Remodeling After Bladder Outlet Obstruction.
Author: LiHong, LiaoBanghua, LiuQiang, LuoDeyi, WangKun-Jie, YangTongxin
Original Abstract of the Article :
BACKGROUND/AIMS: Overactive bladder associated with bladder outlet obstruction (BOO) is a highly prevalent condition, which is usually treated with antimuscarinics. However, the potential effects of antimuscarinics on the structure and function of bladder have not been investigated thus far. METHOD...See full text at original site
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引用元:
https://doi.org/10.1159/000485358
データ提供:米国国立医学図書館(NLM)
Antimuscarinics: Protective Effects on Bladder Remodeling After Bladder Outlet Obstruction
The field of urology is constantly seeking ways to improve the treatment of bladder disorders. This study explores the potential of antimuscarinics, a class of medications commonly used to treat overactive bladder, to protect the bladder from structural and functional changes associated with bladder outlet obstruction (BOO). The researchers investigated the effects of three different antimuscarinics on bladder function and structure in a rat model of BOO. The results suggest that antimuscarinics may offer a protective effect on the bladder, preventing the detrimental changes associated with BOO.
Antimuscarinics: A Potential Protector for the Bladder
This study provides compelling evidence that antimuscarinics can offer a protective effect on the bladder, preventing the detrimental changes associated with BOO. The researchers found that antimuscarinics reduced bladder weight, improved voiding parameters, enhanced bladder smooth muscle contraction, and inhibited the proliferation of bladder smooth muscle cells. These findings suggest that antimuscarinics may play a valuable role in managing BOO and preserving bladder function.
Managing Bladder Disorders: A Holistic Approach
This research highlights the importance of addressing the underlying mechanisms of bladder disorders and developing targeted therapies that protect the bladder from damage. Antimuscarinics, with their potential to mitigate the structural and functional changes associated with BOO, offer a promising avenue for managing this common condition. Remember, a healthy lifestyle, including regular hydration and bladder training exercises, can also play a crucial role in maintaining bladder health. Imagine this as a journey through a vast and sometimes-treacherous desert, where a combination of medication, lifestyle modifications, and proactive care creates a sustainable path towards optimal bladder health.
Dr.Camel's Conclusion
This study provides valuable insights into the potential of antimuscarinics to protect the bladder from the detrimental effects of BOO. The findings offer a promising avenue for managing this common condition and preserving bladder function. This research emphasizes the importance of ongoing research to develop targeted therapies that address the underlying mechanisms of bladder disorders and improve the quality of life for individuals struggling with these conditions.
Date :
- Date Completed 2018-01-18
- Date Revised 2019-02-12
Further Info :
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