Paper Details 
Original Abstract of the Article :
OBJECTIVE: To analyse the adverse drug reactions (ADRs) caused by Sodium-glucose Cotransporter-2 Inhibitors (SGLT2i) notified in Spain since they have been on the market. MATERIAL AND METHODS: An analysis was made of all the notifications registered in the Spanish Pharmacovigilance System of drugs ...See full text at original site
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引用元:
https://doi.org/10.1016/j.semerg.2017.10.003

データ提供:米国国立医学図書館(NLM)

Navigating the Side Effects of SGLT2 Inhibitors: A Pharmacovigilance Study

Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are a class of drugs used to manage type 2 diabetes. While effective in lowering blood sugar levels, SGLT2i can also cause side effects. This research analyzes adverse drug reactions (ADRs) reported to the Spanish Pharmacovigilance System related to the use of SGLT2i. The study found that the most common ADRs were urinary tract infections, diabetic ketoacidosis, and kidney damage. While most urinary tract infections were not serious, ketoacidosis and kidney damage posed significant risks, requiring hospitalization and sometimes even life-threatening interventions.

The Importance of Monitoring and Reporting ADRs

This research underscores the importance of pharmacovigilance systems for monitoring and reporting ADRs related to medications. The findings highlight the potential risks associated with SGLT2i and the need for careful monitoring of patients, particularly those with pre-existing kidney conditions.

Safeguarding Diabetes Management: A Balanced Approach

Managing diabetes is like navigating a desert oasis, with a delicate balance between maintaining blood sugar levels and managing potential risks. This research emphasizes the importance of a cautious approach to SGLT2i therapy, weighing the potential benefits against the risks and closely monitoring patients for any adverse effects.

Dr. Camel's Conclusion

The desert is a place of both beauty and danger, and managing diabetes can feel like navigating a similar landscape. This research helps us understand the potential risks associated with SGLT2i therapy, urging us to proceed with caution and monitor closely for any adverse effects. It's a reminder that even in the pursuit of wellness, we must be vigilant and mindful of the potential pitfalls along the way.

Date :
  1. Date Completed 2018-09-05
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

29183654

DOI: Digital Object Identifier

10.1016/j.semerg.2017.10.003

SNS
PICO Info
in preparation
Languages

Spanish

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