EMA Review of Panobinostat (Farydak) for the Treatment of Adult Patients with Relapsed and/or Refractory Multiple Myeloma.

Author: BerghJonas, De GraeffPieter, FolinAnnika, GisselbrechtChristian, LaaneEdward, LudwigHeinz, PignattiFrancesco, SalmonsonTomas, SjöbergJan, TzoganiKyriaki, WalshIta, van HennikPaula

Paper Details 
Original Abstract of the Article :
On August 28, 2015, a marketing authorization valid through the European Union was issued for panobinostat, in combination with bortezomib and dexamethasone, for the treatment of adult patients with relapsed and/or refractory multiple myeloma who have received at least two prior regimens including b...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947444/

データ提供:米国国立医学図書館(NLM)

Panobinostat: A Powerful Weapon Against Multiple Myeloma

Multiple myeloma, a type of blood cancer, can be a formidable adversary, like a relentless desert sandstorm. This article, like a resourceful desert nomad seeking a remedy for a difficult situation, explores the use of panobinostat in treating relapsed or refractory multiple myeloma. The authors discuss the drug's mechanism of action and the clinical trial data that support its effectiveness.

Panobinostat: A Promising Treatment for Relapsed Myeloma

Panobinostat, like a potent desert plant with medicinal properties, works by inhibiting histone deacetylase (HDAC) enzymes, which are involved in regulating gene expression. This targeted approach, like aiming an arrow at a specific target in the desert, helps to disrupt the growth and spread of myeloma cells. The authors highlight the clinical trial data that demonstrated panobinostat's effectiveness in combination with other therapies.

Understanding the Side Effects: Navigating the Desert's Challenges

The article acknowledges that panobinostat, like many powerful medicines, can cause side effects. These side effects, like the harsh elements of a desert environment, can be a challenge to manage, but they are often outweighed by the benefits of the treatment. The authors provide a detailed overview of the most common side effects and encourage patients to discuss any concerns with their healthcare providers.

Dr. Camel's Conclusion

Panobinostat, like a well-tested oasis in a treacherous desert, offers a glimmer of hope for individuals battling multiple myeloma. It's a testament to the tireless efforts of researchers and clinicians who strive to find new and innovative treatments for this challenging disease. It's a reminder that even in the face of adversity, there is always a chance for progress and healing.

Date :
  1. Date Completed 2019-09-19
  2. Date Revised 2019-09-19
Further Info :

Pubmed ID

29192015

DOI: Digital Object Identifier

PMC5947444

Related Literature

SNS
PICO Info
in preparation
Languages

English

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