Assessment of Tapentadol API Abuse Liability With the Researched Abuse, Diversion and Addiction-Related Surveillance System.

Author: CiceroTheodore J, DartRichard C, GreenJody L, KurtzSteven P, ParrinoMark W, SevertsonS Geoffrey, VosburgSuzanne K

Paper Details 
Original Abstract of the Article :
Tapentadol, a Schedule II opioid with a combination of µ-opioid activity and norepinephrine reuptake inhibition, is used for the management of moderate to severe acute and chronic pain. Its dual mechanism of action is thought to reduce opioid-related side effects that can complicate pain management....See full text at original site
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引用元:
https://doi.org/10.1016/j.jpain.2017.11.007

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Tapentadol Abuse

Tapentadol, a Schedule II opioid, is a powerful medication used for managing pain. Like a skilled desert traveler, we must tread carefully when using this potent drug, as it carries the potential for abuse and addiction. This retrospective cohort study delves into the abuse liability of tapentadol, comparing it to other opioids like tramadol, hydrocodone, and morphine. The authors analyzed data from various sources, including poison centers, drug diversion programs, and treatment centers, to assess the public health burden associated with tapentadol abuse. Their findings suggest that while the abuse rate is relatively low, it is not negligible, highlighting the importance of careful monitoring and responsible use of this medication.

Balancing Pain Relief and Abuse Prevention

This study underscores the importance of finding a balance between providing effective pain relief and preventing drug abuse. The authors emphasize the need for continued surveillance and research to better understand the abuse potential of tapentadol, particularly as new formulations emerge. This research highlights the ongoing challenge of managing the risks and benefits of opioid medications, particularly in the context of the opioid crisis.

The Desert of Opioid Abuse: A Call for Caution

This study reminds us of the dangers of opioid abuse and the importance of responsible prescribing practices. Just as a desert traveler must be cautious of the harsh environment, clinicians need to be aware of the potential risks associated with opioids and take appropriate measures to prevent abuse and addiction. This research is a valuable reminder that the journey through the desert of opioid use requires vigilance and careful navigation.

Dr. Camel's Conclusion

This study is a valuable reminder that the desert of opioid use can be treacherous. Just as a camel must be careful to avoid dehydration and navigate the challenging terrain, clinicians must be mindful of the potential risks associated with opioids. This research is a beacon of awareness in the ongoing fight against the opioid crisis, urging us to approach opioid use with caution and responsibility.

Date :
  1. Date Completed 2019-10-28
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

29224919

DOI: Digital Object Identifier

10.1016/j.jpain.2017.11.007

SNS
PICO Info
in preparation
Languages

English

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