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Treatment of Chronic Pain With Various Buprenorphine Formulations: A Systematic Review of Clinical Studies.

Author: AiyerRohit, BhatiaAnuj, GulatiAmitabh, GungorSemih, MehtaNeel

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review examined the effectiveness of different buprenorphine formulations for managing chronic pain. The review found that transdermal buprenorphine was the most effective formulation, with buccal buprenorphine also showing promise.
Paper Details　
Original Abstract of the Article :
Clinical studies demonstrate that buprenorphine is a pharmacologic agent that can be used for the treatment of various types of painful conditions. This study investigated the efficacy of 5 different types of buprenorphine formulations in the chronic pain population. The literature was reviewed on P...See full text at original site
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引用元：
https://doi.org/10.1213/ANE.0000000000002718

データ提供：米国国立医学図書館（NLM）

Buprenorphine Formulations for Chronic Pain: A Comprehensive Review

The management of chronic pain is a complex challenge, with researchers continually seeking safer and more effective treatment options. This research investigates the efficacy of various buprenorphine formulations for treating chronic pain. The authors conducted a systematic review of clinical trials, evaluating the effectiveness and safety of different buprenorphine formulations in managing chronic pain.

Transdermal Buprenorphine Emerges as a Promising Option

The review of 25 randomized controlled trials revealed that transdermal buprenorphine demonstrated significant pain reduction in patients with chronic pain. While buccal buprenorphine also showed promise, further research is needed to confirm its efficacy. Importantly, no serious adverse effects were reported in any of the studies.

A New Hope for Chronic Pain Management

These findings provide valuable insights into the potential of buprenorphine formulations, particularly transdermal buprenorphine, in managing chronic pain. This research paves the way for developing more targeted and effective treatments, offering hope for individuals struggling with chronic pain.

Dr. Camel's Conclusion

This research sheds light on the potential of buprenorphine formulations for alleviating chronic pain. Transdermal buprenorphine appears to be a promising option for chronic pain management, with a favorable safety profile. It's crucial to remember that pain management is a complex process, and individual responses to treatments can vary.

Date :
  1. Date Completed 2019-08-16
  2. Date Revised 2019-08-16
Further Info :

Pubmed ID

29239947

DOI: Digital Object Identifier

10.1213/ANE.0000000000002718

Related Literature

Article Analysis
・Effects of buprenorphine buccal (chronic pain)
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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