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Drug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment.

Author: BazinDominique, DaudonMichel, FrochotVincent, JungersPaul

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Drug-induced renal calculi represent 1-2% of all cases. The drugs causing calculi can be divided into two groups: 1) poorly soluble drugs that crystallize in the urine, and 2) drugs that alter urinary pH or excretion of components like calcium, phosphate, or oxalate. This article discusses the most common drug culprits in each group and methods for diagnosis and prevention.
Paper Details　
Original Abstract of the Article :
Drug-induced calculi represent 1-2% of all renal calculi. The drugs reported to produce calculi may be divided into two groups. The first one includes poorly soluble drugs with high urine excretion that favour crystallisation in the urine. Among them, drugs used for the treatment of patients with hu...See full text at original site
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引用元：
https://doi.org/10.1007/s40265-017-0853-7

データ提供：米国国立医学図書館（NLM）

Navigating the Complexities of Drug-Induced Kidney Stones

In the realm of [nephrology], the formation of [kidney stones] poses a significant challenge, and [drug-induced calculi] represent a subset of this condition. This comprehensive review delves into the [pathophysiology, prevention, and treatment] of [drug-induced kidney stones and crystalline nephropathy].

Drug-Induced Calculi: A Diverse Landscape

The authors categorize [drugs] that induce [kidney stones] into two distinct groups: [poorly soluble drugs] and [drugs that alter urinary metabolism]. The study provides an insightful overview of the [mechanisms] by which these medications can contribute to [stone formation] and [acute renal failure].

The Importance of Careful Medication Management

Like a vigilant camel navigating a treacherous desert, we must approach medication management with careful consideration. This review highlights the importance of [awareness] of potential [drug-induced adverse effects], including [kidney stone formation]. It emphasizes the need for [proper diagnosis, prevention, and treatment] to mitigate these risks.

Dr.Camel's Conclusion

This comprehensive review offers invaluable insights into the complexities of drug-induced kidney stones and crystalline nephropathy. The authors provide a detailed overview of the underlying mechanisms, preventive measures, and treatment strategies, empowering healthcare professionals and patients to navigate this challenging condition. Just as a camel relies on its instincts to navigate the desert's unpredictable terrain, we must be aware of potential risks and proactive in our approach to medication management.
Date :
  1. Date Completed 2019-04-03
  2. Date Revised 2019-04-03
Further Info :

Pubmed ID

29264783

DOI: Digital Object Identifier

10.1007/s40265-017-0853-7

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English

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