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Esmya<sup>&#174;</sup> and the PEARL studies: A review.

Author: DuttaDeborata, PowellMartin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Ulipristal acetate is effective in treating heavy menstrual bleeding associated with uterine fibroids, with a favorable side-effect profile compared to leuprorelin acetate. It decreased fibroid volume and improved bleeding control.
Paper Details　
Original Abstract of the Article :
Ulipristal acetate was investigated in four phase 3 trials. In PEARL I, ulipristal produced significant normalisation of blood loss within 1 week and decreased fibroid volume. In PEARL II, ulipristal produced faster and more consistent control of bleeding than leuprorelin acetate and had a more favo...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373264/

データ提供：米国国立医学図書館（NLM）

Ulipristal Acetate: A Promising Treatment for Uterine Fibroids

This review examines the effectiveness of ulipristal acetate, a medication used to treat uterine fibroids, benign tumors that can cause heavy bleeding and pain. It's like exploring a hidden treasure in the depths of the human body, finding a solution to a common but often debilitating condition. This review summarizes the results of four phase 3 clinical trials, highlighting the potential benefits of ulipristal acetate in managing uterine fibroids.

A New Oasis: Ulipristal Acetate for Fibroids

The review indicates that ulipristal acetate effectively reduced bleeding and fibroid volume in patients with uterine fibroids. It's like discovering a hidden oasis in a barren desert, offering a much-needed source of relief. The medication also had a favorable side effect profile compared to other treatment options. This review provides valuable information for healthcare providers seeking to offer effective and well-tolerated treatment options for patients with uterine fibroids.

Finding Relief from Fibroids: A New Hope

This review provides hope for patients struggling with uterine fibroids. It's like finding a hidden path through the desert, leading to a more comfortable and fulfilling life. Ulipristal acetate appears to be a promising treatment option, offering relief from heavy bleeding, pain, and other symptoms associated with fibroids.

Dr.Camel's Conclusion

This review highlights the potential of ulipristal acetate as a safe and effective treatment for uterine fibroids. It's like finding a new oasis in the desert, offering a much-needed source of relief for patients struggling with this condition. Further research is needed to explore the long-term benefits and potential risks of ulipristal acetate, but the initial findings are promising.

Date :
  1. Date Completed 2018-04-13
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

29334010

DOI: Digital Object Identifier

PMC5373264

Related Literature

Article Analysis
・Side Effects of ulipristal
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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