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Original Abstract of the Article :
BACKGROUND: Cases of pancreatitis were identified in the eluxadoline clinical development program, reflected in initial product labelling, and the subject of postmarketing reports. AIM: To analyse postmarketing cases of eluxadoline-associated pancreatitis. METHODS: We retrospectively analysed all ...See full text at original site
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引用元:
https://doi.org/10.1111/apt.14504
データ提供:米国国立医学図書館(NLM)
Eluxadoline and Pancreatitis: Navigating a Potential Side Effect
Understanding the potential side effects of medications is crucial for safe and effective treatment. This analysis of postmarketing cases examines the association between eluxadoline, a medication used for irritable bowel syndrome with diarrhea, and pancreatitis. Researchers reviewed reports of pancreatitis associated with eluxadoline, revealing a potential risk, particularly for individuals without a gallbladder. This information is crucial for informing clinical practice and ensuring patient safety.
Eluxadoline and Pancreatitis: A Desert Crossing with Caution
The analysis revealed that patients without a gallbladder were overrepresented among those who developed eluxadoline-associated pancreatitis, despite receiving the recommended lower dose. This finding highlights the need for careful monitoring and consideration of individual risk factors when prescribing eluxadoline. It's like navigating a desert crossing, requiring careful planning, attention to potential hazards, and a willingness to adjust course as needed.
Informed Decision-Making: Essential for Patient Safety
The study emphasizes the importance of informed decision-making when prescribing medications. Healthcare providers should carefully weigh the potential benefits and risks of eluxadoline, considering individual patient characteristics, such as the presence or absence of a gallbladder, to minimize the risk of pancreatitis. It's like choosing the right path through the desert, taking into account the terrain, weather conditions, and potential dangers to ensure a safe journey.
Dr.Camel's Conclusion
This analysis highlights the importance of postmarketing surveillance to identify potential drug-related side effects and inform clinical practice. The findings regarding eluxadoline and pancreatitis underscore the need for careful monitoring and informed decision-making when prescribing medications, ensuring patient safety and optimizing therapeutic outcomes.
Date :
- Date Completed 2019-06-12
- Date Revised 2019-06-13
Further Info :
Related Literature
English
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