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A Phase II, Randomized, Double-Blind Clinical Study Evaluating the Safety, Tolerability, and Efficacy of a Topical Minocycline Foam, FMX103, for the Treatment of Facial Papulopustular Rosacea.
Author: EiniMeir, KedemTal Hetzroni, KeynanRita, MrowietzUlrich, RomDror, ShirvanMitchell, TamarkinDov
Original Abstract of the Article :
OBJECTIVE: Our objective was to demonstrate the safety, tolerability, and efficacy of a minocycline foam, FMX103, in the treatment of moderate-to-severe facial papulopustular rosacea. METHODS: This was a phase II, randomized, double-blind, multicenter study. Healthy subjects aged ≥ 18 years with mo...See full text at original site
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引用元:
https://doi.org/10.1007/s40257-017-0339-0
データ提供:米国国立医学図書館(NLM)
Topical Minocycline Foam for Facial Papulopustular Rosacea: A Phase II Trial
Rosacea, a common skin condition characterized by facial redness, bumps, and pustules, can significantly impact quality of life. This phase II trial investigates the safety, tolerability, and efficacy of a topical minocycline foam, FMX103, in treating moderate to severe facial papulopustular rosacea. The researchers conducted a randomized, double-blind, multicenter study comparing the effects of 1.5% and 3% FMX103 to a vehicle control. The study found that both 1.5% and 3% FMX103 significantly reduced inflammatory lesion counts and improved overall rosacea severity compared to the vehicle control. The treatment was generally well-tolerated, with few adverse events reported. These findings suggest that topical minocycline foam may be a promising new treatment option for moderate to severe facial papulopustular rosacea.Topical Minocycline Foam: A Potential Breakthrough for Rosacea Management
This phase II trial provides encouraging evidence for the efficacy and safety of topical minocycline foam in treating facial papulopustular rosacea. These findings warrant further investigation in larger phase III trials to confirm the long-term efficacy and safety of this treatment modality.Navigating the Landscape of Skin Health
Rosacea, like a persistent desert wind, can be a source of discomfort and frustration for those affected. This research offers a glimmer of hope, highlighting the potential of topical minocycline foam to provide relief and improve the lives of individuals with rosacea.Dr.Camel's Conclusion
Rosacea, like a prickly cactus, can be a challenging and persistent skin condition. This research offers a promising path forward, highlighting the potential of topical minocycline foam to provide effective and well-tolerated treatment for facial papulopustular rosacea. As we continue to explore the intricacies of skin health, we can uncover even more innovative solutions to address the diverse needs of those seeking relief from skin conditions.Date :
- Date Completed 2018-10-01
- Date Revised 2018-10-01
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