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Health-related quality of life on the clinical course of patients with chronic hepatitis C receiving daclatasvir/asunaprevir therapy: A prospective observational study comparing younger (<70) and elderly (≥70) patients.
Author: AbeHiroko, FukazawaTakako, HasegawaErina, HirosawaHiroshi, HirosawaShiori, IshikawaToru, KobayashiMiki, KoyamaFujiko, MaruyamaYuka, NakanoTomomi, NoguchiHirohito, OhashiKazuki, SatoKaede, SuzukiMitsuyuki, UekiAya, YoshidaToshiaki
Original Abstract of the Article :
Interferon-free direct acting antiviral agent regimens for chronic hepatitis C (CHC) have been developed. These regimens have shown a high rate of sustained virologic response (SVR), and a reduction in side effects during treatment is also anticipated. However, the impact of the regimens on health-r...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772754/
データ提供:米国国立医学図書館(NLM)
Daclatasvir/Asunaprevir: A Hopeful Treatment for Chronic Hepatitis C
In the ongoing fight against chronic hepatitis C (CHC), interferon-free direct acting antiviral agents (DAAs) have revolutionized treatment. This study evaluated the impact of daclatasvir/asunaprevir (DCV/ASV) therapy on health-related quality of life (HRQOL) in CHC patients. Researchers prospectively observed 28 patients receiving DCV/ASV therapy, measuring HRQOL using the Short Form-36 (SF-36) method. The study found that DCV/ASV therapy significantly improved liver function parameters, including aspartate aminotransferase, alanine aminotransferase, serum albumin, and Fibrosis-4 index. Additionally, the therapy led to significant improvements in HRQOL, particularly among elderly patients (≥70 years old).DCV/ASV Therapy: A Positive Impact on HRQOL
The study's findings suggest that DCV/ASV therapy not only effectively treats CHC but also improves HRQOL, especially in elderly patients. The observed improvements in liver function and overall well-being contribute to a better quality of life for patients with CHC. This research underscores the positive impact of DAAs on both physical and mental health.Navigating CHC Treatment: A Personalized Approach
This research highlights the importance of individualized approaches to CHC treatment. While DCV/ASV therapy demonstrated promising results, it's crucial to consider patient factors, such as age, overall health, and treatment preferences. Consulting with a healthcare professional to develop a personalized treatment plan is essential for maximizing the benefits and minimizing potential risks associated with CHC therapy.Dr. Camel's Conclusion
My dear friends, the desert of CHC can be a challenging landscape to navigate. This study highlights the promise of DCV/ASV therapy, which not only clears the virus but also improves the overall well-being of patients. Remember, just as a camel finds strength in its endurance, CHC patients can find hope and resilience through effective treatment and personalized care. Let's continue to explore new pathways in the desert of CHC, striving for better outcomes and a brighter future for all affected by this disease.Date :
- Date Completed n.d.
- Date Revised 2020-09-29
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