Paper Details 
Original Abstract of the Article :
Multidrug resistance, mediated by members of the ATP-binding cassette (ABC) proteins superfamily, has become one of the biggest obstacles in conquering tumour progression. If the chemotherapy outcome is considered successful, when the primary tumour volume is decreased or completely abolished, modul...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017720/

データ提供:米国国立医学図書館(NLM)

The Labyrinth of Multidrug Resistance in Cancer: Navigating the Desert of Treatment

This research delves into the complex world of multidrug resistance (MDR), a major challenge in cancer therapy. The study explores the role of ATP-binding cassette (ABC) proteins, which act as pumps that can expel chemotherapy drugs from cancer cells, leading to treatment failure. The researchers discuss the limitations of current strategies for overcoming MDR and emphasize the need for a deeper understanding of the complex interplay between ABC proteins and cancer progression.

A Labyrinth of Resistance: The Desert of Cancer Treatment

The study highlights the challenges posed by MDR, where cancer cells develop mechanisms to evade the effects of chemotherapy drugs. It's like navigating a labyrinth, where every turn presents a new obstacle. This research delves into the intricacies of ABC proteins, which act as gatekeepers, preventing chemotherapy drugs from reaching their target. It's like a desert landscape, where every sand dune presents a new challenge for those seeking to reach their destination.

A Desert Oasis of Hope: Finding New Strategies for Cancer Treatment

This research underscores the need for a multi-pronged approach to overcoming MDR in cancer. It emphasizes the importance of developing novel strategies that can target ABC proteins and disrupt their activity, thereby restoring the effectiveness of chemotherapy. It's like seeking a desert oasis, where finding a new source of water can revitalize the journey and offer a chance for survival.

Dr.Camel's Conclusion

This study is like a map through the labyrinth of multidrug resistance in cancer, providing valuable insights into the complex interplay between ABC proteins and cancer progression. It offers hope for the development of new strategies that can overcome resistance and improve the effectiveness of cancer therapies.

Date :
  1. Date Completed 2018-08-10
  2. Date Revised 2018-12-07
Further Info :

Pubmed ID

29401721

DOI: Digital Object Identifier

PMC6017720

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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