Repeated intraocular crystallization of ganciclovir in one eye after bilateral intravitreal injections: a case report.

Author: FanMichelle C Y, IuLawrence P L, LamWai-Ching, WongIan Y H

Paper Details 
Original Abstract of the Article :
Cytomegalovirus (CMV) retinitis is an opportunistic infection that primarily affects immunocompromised individuals. Intravitreal ganciclovir injection monotherapy or in combination with systemic anti-CMV therapy are effective treatments for CMV retinitis. Crystallization of ganciclovir after intravi...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807747/

データ提供:米国国立医学図書館(NLM)

Ganciclovir Crystallization: A Rare Occurrence

This research delves into the fascinating yet uncommon world of ganciclovir crystallization, a complication that can arise after intravitreal injections. It's like finding a shimmering oasis in the vast desert of medical knowledge! This study examines the case of a patient who experienced ganciclovir crystallization in one eye after bilateral injections, a phenomenon that had never been reported before. The authors meticulously document the repeated crystallization in the same eye after subsequent injections, shedding light on the complexities of this rare occurrence. Their findings contribute to our understanding of ganciclovir's behavior within the eye and highlight the importance of monitoring for potential complications.

A New Perspective on a Familiar Drug

This research shines a light on the unexpected side effects that can arise from even well-established medications. We often think of drugs as predictable tools, but this case reminds us that there's always more to learn about their interactions with our bodies. The study's detailed analysis of the patient's experience provides valuable insights into the intricate dance between medication and the human body.

Implications for Clinical Practice

This study serves as a cautionary tale for clinicians, urging them to remain vigilant for even the rarest of complications. It emphasizes the need for meticulous observation and the importance of staying abreast of emerging knowledge in the field of ophthalmology. The authors emphasize the need for careful monitoring and further research to enhance our understanding of this rare complication.

Dr.Camel's Conclusion

This research is a reminder that even seemingly well-understood medications can present surprising challenges, like finding a hidden oasis in a familiar desert. The authors' meticulous documentation of this unique case provides valuable insights into the complexities of ganciclovir's behavior within the eye and highlights the importance of vigilance in clinical practice.

Date :
  1. Date Completed 2018-02-16
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

29426296

DOI: Digital Object Identifier

PMC5807747

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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