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Role of immunotherapy in bacillus Calmette-Guérin-unresponsive non-muscle invasive bladder cancer.
Author: MansourAhmed M, MukherjeeNeelam, SvatekRobert S
Original Abstract of the Article :
Intravesical instillation of live attenuated bacillus Calmette-Guérin (BCG) is the gold standard for patients with intermediate- and high-risk non-muscle-invasive bladder cancer (NMIBC). BCG-failures include a heterogenous population of patients who share a designation of disease recurrence or progr...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/29429897
データ提供:米国国立医学図書館(NLM)
Immunotherapy: A New Oasis in the Desert of Bladder Cancer
Bladder cancer, a challenging disease, is like a stubborn desert sandstorm, difficult to control. Intravesical instillation of bacillus Calmette-Guérin (BCG), a standard treatment for non-muscle-invasive bladder cancer (NMIBC), is often ineffective for some patients. This study examines the potential of immunotherapy, a promising approach for treating cancer, in patients with BCG-unresponsive NMIBC.
Immunotherapy: A Potential Solution for BCG-Unresponsive Bladder Cancer
The study explores the potential of immune checkpoint inhibitors, a type of immunotherapy that boosts the immune system's ability to fight cancer, for treating patients with BCG-unresponsive NMIBC. While the data supporting this approach is limited, the study highlights the potential of these inhibitors based on theoretical evidence and observed increased PD-L1 expression in BCG-unresponsive tumors. Clinical trials are currently underway to evaluate the effectiveness of immunotherapy in this challenging patient population.
Navigating the Desert of Bladder Cancer: Exploring New Treatment Strategies
This study underscores the need for innovative treatment strategies for patients with BCG-unresponsive NMIBC. Immunotherapy, with its ability to harness the power of the immune system, offers a promising new approach to combatting this stubborn disease. Further research and clinical trials are crucial to determine the efficacy and safety of immunotherapy for this patient population.
Dr. Camel's Conclusion
This study offers a ray of hope in the desert of bladder cancer. Immunotherapy, with its potential to enhance the immune system's fight against cancer, holds promise for patients with BCG-unresponsive NMIBC. Continued research and clinical trials are essential to unlock the full potential of immunotherapy and provide effective treatment options for this challenging disease.
Date :
- Date Completed 2018-10-24
- Date Revised 2022-03-30
Further Info :
Related Literature
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