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Cardiovascular safety of prokinetic agents: A focus on drug-induced arrhythmias.
Author: AckermanM J, CamilleriM, GiudicessiJ R
Original Abstract of the Article :
Gastrointestinal sensorimotor dysfunction underlies a wide range of esophageal, gastric, and intestinal motility and functional disorders that collectively constitute nearly half of all referrals to gastroenterologists. As a result, substantial effort has been dedicated toward the development of pro...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/29441683
データ提供:米国国立医学図書館(NLM)
Cardiovascular Safety of Prokinetic Agents: A Balancing Act
Gastrointestinal motility disorders can significantly impact quality of life, and prokinetic agents are often prescribed to improve digestive function. However, some of these agents have been associated with adverse cardiovascular effects. This research examines the cardiovascular safety profile of prokinetic agents, focusing on drug-induced arrhythmias, a type of irregular heartbeat that can be life-threatening.
The study reviews the cardiovascular safety profiles of various prokinetic agents, including cisapride, domperidone, erythromycin, and tegaserod. The study highlights the potential for these drugs to induce arrhythmias, leading to restrictions in their use. The study emphasizes the importance of careful patient selection, monitoring for adverse effects, and considering alternative treatment options when necessary. It's like a camel caravan navigating a desert, where each step must be taken with caution and awareness of the potential dangers.
Prokinetic Agents: Balancing Benefits and Risks
The research highlights the delicate balance between the therapeutic benefits and potential cardiovascular risks of prokinetic agents. It emphasizes the need for clinicians to carefully weigh the potential benefits and risks for each patient, considering their individual cardiovascular health and other factors. It's like a wise camel rider, carefully assessing the terrain and choosing the safest path to reach their destination.
Navigating the Complexities of Gastrointestinal Motility Disorders
This research underscores the importance of a comprehensive understanding of gastrointestinal motility disorders and the potential cardiovascular effects of prokinetic agents. It encourages ongoing research to develop safer and more effective treatments for these conditions while minimizing the risk of adverse cardiovascular events. It's like a camel caravan, equipped with a map and a compass, navigating the vast and complex desert of medical science.
Dr.Camel's Conclusion
This research reminds us that the desert of medical innovation is vast and full of complexities. As we strive to develop new and effective treatments, we must also prioritize patient safety and carefully consider the potential risks associated with medication. It's like a wise camel, utilizing its knowledge of the desert to navigate safely and efficiently, seeking to find the best solutions for human health.
Date :
- Date Completed 2019-10-17
- Date Revised 2020-03-06
Further Info :
Related Literature
English
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