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Drug-induced QT Interval Prolongation in the Intensive Care Unit.

Author: ChengSixuan, Di GirolamoGuillermo, EtchegoyenCecilia Villa, KellerGuillermo Alberto, MradSebastian

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study addresses drug-induced QT interval prolongation, the most common acquired cause of Long QT syndrome (LQTS), which is characterized by an extended duration of the ventricular repolarization. This syndrome increases the risk for polymorphic ventricular tachycardia and sudden death.
Paper Details　
Original Abstract of the Article :
The most common acquired cause of Long QT syndrome (LQTS) is drug induced QT interval prolongation. It is an electrophysiological entity, which is characterized by an extended duration of the ventricular repolarization. Reflected as a prolonged QT interval in a surface ECG, this syndrome increases t...See full text at original site
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引用元：
https://doi.org/10.2174/1574884713666180223123947

データ提供：米国国立医学図書館（NLM）

Drug-Induced QT Interval Prolongation: A Ticking Time Bomb in the ICU

The world of critical care, my friends, is a complex landscape. Imagine the ICU as a vast desert, with each patient a unique oasis, each needing special care. One critical challenge in this arid landscape is drug-induced QT interval prolongation. This research delves into the complexities of this condition, exploring its electrophysiological nature and the potential for sudden death. The authors utilize a comprehensive approach, drawing on insights from surface ECGs and examining the interplay of drug interactions and the delicate rhythm of the heart. This research illuminates a critical aspect of patient care, especially in the high-stakes environment of the ICU.

A Prolonged QT Interval: A Sign of a Troubled Heartbeat

This study emphasizes the importance of understanding the potential risks associated with certain medications. It highlights the delicate balance between the therapeutic benefits of drugs and their potential to disrupt the normal rhythm of the heart. A prolonged QT interval can be a silent warning, a hidden tremor in the sand dunes of the body's rhythm. The authors paint a vivid picture of this complex medical phenomenon, revealing the dangers of ignoring this potential threat.

Navigating the Desert of Drug Interactions: A Guide for Clinicians

The researchers caution us to be mindful of the potential risks associated with drug-induced QT interval prolongation. The desert of the human body is full of hidden dangers, including the potential for unforeseen drug interactions. This research serves as a valuable guide for clinicians, offering critical insights into the management of this potentially life-threatening condition.

Dr. Camel's Conclusion

Drug-induced QT interval prolongation is a silent threat lurking in the ICU. This study sheds light on the importance of carefully monitoring patients for this condition, especially those receiving multiple medications. It emphasizes the crucial role of vigilance in protecting patients from the hazards of drug interactions. In the vast desert of critical care, knowledge is our compass, guiding us towards safer and more effective treatments.

Date :
  1. Date Completed 2019-04-11
  2. Date Revised 2019-04-11
Further Info :

Pubmed ID

29473523

DOI: Digital Object Identifier

10.2174/1574884713666180223123947

SNS
PICO Info
in preparation
Languages

English

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