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The effects of taxanes, vorinostat and doxorubicin on growth and proliferation of <i>Echinococcus multilocularis</i> metacestodes assessed with magnetic resonance imaging and simultaneous positron emission tomography.
Author: GrünerBeate, HoffmannWolfgang, HuangXiangsheng, KöhlerCarsten, SoboslayPeter T, VoßbergPatrick, WiehrStefan, WildAnna-Maria
Original Abstract of the Article :
Cytostatic drugs used in cancer therapy were evaluated for their capacity to inhibit <i>Echinococcus multilocularis</i> metacestode growth and proliferation. Metacestode tissues were exposed <i>in vitro</i> to docetaxel, doxorubicin, navelbine, paclitaxel, and vorinostat for 1 week, then incubated i...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823665/
データ提供:米国国立医学図書館(NLM)
Echinococcus multilocularis: A Persistent Desert Sandworm
Echinococcus multilocularis, like a persistent desert sandworm, can burrow deep into the body, causing a parasitic infection known as alveolar echinococcosis. This study, like a dedicated researcher, investigates the effects of various cytotoxic drugs on the growth and proliferation of this elusive parasite.
The researchers exposed E. multilocularis metacestodes to docetaxel, doxorubicin, navelbine, paclitaxel, and vorinostat, a collection of drugs akin to a potent arsenal against the sandworm. They found that docetaxel, like a targeted missile, demonstrated the most significant inhibitory effect on parasite growth and proliferation both in vitro and in vivo.
A New Weapon in the Fight Against Echinococcus multilocularis
This study suggests that docetaxel, like a beacon of hope in the desert, may be a valuable new weapon in the fight against alveolar echinococcosis. The findings provide encouraging evidence for further research and development of targeted therapies against this parasitic infection.
Navigating the Desert of Parasitic Infections: A Call for Innovation
This research underscores the need for innovative approaches to combat parasitic infections. By exploring new drugs and treatment strategies, we can develop more effective interventions and improve patient outcomes. This journey, like a camel caravan traversing the vast desert, requires perseverance, creativity, and a commitment to finding solutions.
Dr. Camel's Conclusion
This study highlights the potential of docetaxel as a promising therapeutic agent against Echinococcus multilocularis. The findings provide a glimmer of hope in the desert of parasitic infections, and underscore the importance of continued research and development of targeted therapies to combat these elusive and often challenging conditions.
Date :
- Date Completed n.d.
- Date Revised 2019-11-20
Further Info :
Related Literature
English
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