Emerging pharmacotherapies for the treatment of atrial fibrillation.

Author: CapucciAlessandro, CipollettaLaura, GianniniIrene, GuerraFederico

Paper Details 
Original Abstract of the Article :
The main aim of current research on the field of atrial fibrillation (AF) treatment is to find new antiarrhythmic drugs with less side effects. Areas covered: Dronedarone and vernakalant showed promising result in term of efficacy and safety in selected patients. Ranolazine and colchicine are obtain...See full text at original site
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引用元:
https://doi.org/10.1080/14728214.2018.1446941

データ提供:米国国立医学図書館(NLM)

Emerging Pharmacotherapies for Atrial Fibrillation

This review explores the exciting landscape of [atrial fibrillation] research, focusing on the development of novel antiarrhythmic drugs with improved safety profiles. The review highlights the potential of several promising candidates, including dronedarone, vernakalant, ranolazine, colchicine, and ivabradine, in the treatment of AF. It also discusses the potential of monoclonal antibodies and selective antagonists of potassium channels for long-term maintenance of sinus rhythm.

A Quest for Safer and More Effective Antiarrhythmic Drugs

The quest for safer and more effective antiarrhythmic drugs for AF is a paramount challenge in [cardiology] research. This review underscores the ongoing efforts to identify new drug candidates that can minimize side effects while effectively managing AF. The authors critically assess the clinical evidence and new pharmacological investigations on several promising drugs, including dronedarone, vernakalant, ranolazine, and colchicine. The review highlights the need for further research to evaluate the long-term efficacy and safety of these drugs in patients with different characteristics and risk factors.

Navigating the Desert of Atrial Fibrillation Treatment

Think of AF as a shifting desert landscape, presenting a unique challenge for clinicians. Finding the right therapeutic approach is like navigating through a vast and complex terrain. This review acts as a compass, guiding researchers through the diverse landscape of potential treatments for AF. The findings suggest that the future of AF management lies in the development of innovative drugs that target specific mechanisms of the disease, minimizing adverse effects and improving the quality of life for patients.

Dr. Camel's Conclusion

The search for effective and safe treatments for atrial fibrillation is like a tireless camel caravan journeying across a scorching desert. This review meticulously examines the latest advancements in the field, highlighting the promising potential of new drug candidates. The research emphasizes the importance of a multi-pronged approach that addresses the unique challenges of this complex heart condition. As a researcher, I remain optimistic that the innovative approaches outlined in this review will pave the way for a brighter future for individuals struggling with AF.
Date :
  1. Date Completed 2018-09-17
  2. Date Revised 2018-09-17
Further Info :

Pubmed ID

29508636

DOI: Digital Object Identifier

10.1080/14728214.2018.1446941

Related Literature

SNS
PICO Info
in preparation
Languages

English

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