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Effect of everolimus on skin lesions in patients treated for subependymal giant cell astrocytoma and renal angiomyolipoma: final 4-year results from the randomized EXIST-1 and EXIST-2 studies.
Author: BelousovaE, BerkowitzN, BisslerJ J, BuddeK, FranzD N, KingswoodJ C, RidolfiA, SparaganaS, de VriesP J
Original Abstract of the Article :
Tuberous sclerosis complex (TSC) is a genetic disorder associated with tumour growth in various organs, including the brain, kidneys, heart and skin. Cutaneous lesions are prevalent manifestations of TSC, occurring in up to 90% of patients. Oral mammalian target of rapamycin inhibitors, such as ever...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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引用元:
https://doi.org/10.1111/jdv.14964
データ提供:米国国立医学図書館(NLM)
Targeting Skin Lesions in Tuberous Sclerosis Complex
The world of medicine is constantly evolving, and the treatment of genetic disorders is a fascinating area of research. This study delves into the realm of Tuberous Sclerosis Complex (TSC), a genetic disorder that can manifest in various organs, including the skin. Imagine a vast, scorching desert, and imagine that the TSC is a hidden oasis within it. This oasis, however, is not always welcoming, as it can sometimes be infiltrated by unwanted growth, like a sandstorm. The researchers investigated the effectiveness of everolimus, a medication, as a treatment for these unwanted growths. Their goal was to determine if everolimus could help control and potentially reverse the impact of TSC on the skin, thus bringing balance to the oasis.
Everolimus's Promise in TSC Treatment
The study's results are promising, suggesting that everolimus could be a valuable tool in treating TSC-associated skin lesions. It's like discovering a new, reliable source of water in the desert, helping the oasis flourish. The researchers found that everolimus effectively targeted the root cause of TSC, which is a remarkable feat akin to finding the source of a desert spring and harnessing its life-giving powers.
A Beacon of Hope for TSC Patients
This research provides hope for individuals with TSC, offering them a potentially effective treatment option to address the skin lesions associated with this condition. It's like discovering a new method for creating a lush oasis in the desert, providing a haven of comfort and relief from the harsh conditions.
Dr.Camel's Conclusion
This study provides valuable insights into the potential of everolimus for treating TSC-associated skin lesions. It's like discovering a secret oasis in the vast desert, offering a haven of hope for individuals battling TSC. Further research is needed to fully understand the long-term effects of everolimus and explore its potential in treating other TSC-related manifestations. As we continue to explore this area of research, we are one step closer to finding solutions for this challenging genetic disorder.
Date :
- Date Completed 2019-01-25
- Date Revised 2019-01-25
Further Info :
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