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Tapentadol Extended Release in the Treatment of Severe Chronic Low Back Pain and Osteoarthritis Pain.

Author: BisneyJohn, LeQuangJo Ann, PergolizziJoseph V, RaffaRobert B, TaylorRobert

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This article examines the potential of tapentadol, a novel pain reliever with dual mechanisms of action, for managing severe chronic pain associated with low back pain (LBP) and osteoarthritis (OA). Tapentadol exhibits efficacy comparable to oxycodone in managing severe chronic LBP and OA pain, and it may offer better tolerability, particularly with respect to gastrointestinal side effects, compared to other strong opioids. The article suggests that tapentadol holds promise as a safe and effective therapeutic option for patients with these chronic pain conditions.
Paper Details　
Original Abstract of the Article :
Tapentadol is a novel pain reliever with apparently synergistic dual mechanisms of action, capable of addressing both nociceptive and neuropathic components of chronic pain. As an effective analgesic with good tolerability, tapentadol may be appropriate for patients suffering from severe chronic pai...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993688/

データ提供：米国国立医学図書館（NLM）

Tapentadol Extended Release for Chronic Pain: A Promising New Option

This study examines the use of [tapentadol extended release] for the management of [severe chronic low back pain and osteoarthritis pain]. Researchers assessed the efficacy and tolerability of tapentadol in comparison to other pain medications, finding that it is a [non-inferior] option to [oxycodone]. The study highlights tapentadol's potential as a safe and effective treatment option for chronic pain, especially in terms of its [favorable gastrointestinal (GI) tolerability].

A Oasis in the Desert of Chronic Pain

Living with chronic pain can be like navigating a desert of suffering, where finding relief can feel like finding a precious oasis. This study explores the potential of tapentadol extended release as a new treatment option for chronic low back pain and osteoarthritis pain. Researchers found that it is non-inferior to oxycodone, a commonly prescribed opioid, but with a better GI tolerability profile. This is significant, as GI side effects are a common concern with opioid medications.

Navigating the Desert of Pain Relief

This research provides valuable information for individuals seeking effective and well-tolerated pain relief. It's like finding a new path through the desert of chronic pain, leading to a more comfortable and manageable journey. Tapentadol extended release offers a promising new option for those struggling with severe chronic pain.

Dr. Camel's Conclusion

This study highlights the potential of tapentadol extended release as a safe and effective treatment option for chronic pain. It's like finding a hidden oasis in the desert of pain, offering relief and improved quality of life for those struggling with chronic low back pain and osteoarthritis pain.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

29623654

DOI: Digital Object Identifier

PMC5993688

Related Literature

Article Analysis
・Side Effects of tapentadol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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