Colonic Mucosal Ulceration and Gastrointestinal Bleeding Associated with Sevelamer Crystal Deposition in a Patient with End Stage Renal Disease.

Author: DevasahayamJoe, KarippotAsha, NambiarSudheer, OliverTony, PillaiUnnikrishnan Kunjan

Paper Details 
Original Abstract of the Article :
End stage renal disease (ESRD) population account for 1.9 per patient year of hospital admissions annually. ESRD population are at increased risk of bleeding secondary to use of anticoagulation during hemodialysis and uremia induced platelet dysfunction. Gastrointestinal bleeding accounts for 3-7% o...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851163/

データ提供:米国国立医学図書館(NLM)

The Unexpected Culprit: Sevelamer and Gastrointestinal Bleeding

Imagine a vast, scorching desert, where the seemingly harmless sand can cause unexpected complications. This research takes us to the world of end-stage renal disease (ESRD), where patients often rely on medication like sevelamer to control phosphate levels. However, this seemingly benign drug can have surprising side effects, as evidenced by a case study presented in this research. The researchers report a unique case of a 56-year-old woman with ESRD who experienced gastrointestinal bleeding. Further examination revealed that sevelamer crystals had deposited in her colonic mucosa, leading to ulceration. This discovery shines a light on an underrecognized consequence of sevelamer use, prompting a call for increased awareness among healthcare providers.

Unveiling the Hidden Dangers of Sevelamer

This case report serves as a stark reminder that even seemingly safe medications can have unexpected consequences. The researchers urge healthcare providers to consider sevelamer-induced mucosal ulceration and crystal deposition as a potential cause of gastrointestinal bleeding in ESRD patients. It's like finding a hidden oasis in a desert, only to discover it's a mirage. The study prompts us to carefully consider the potential risks associated with medications, even those widely used.

Navigating the Sands of ESRD

The findings underscore the importance of vigilant monitoring for potential complications, even with commonly used medications. It's like navigating a desert, where every step must be taken with caution. The study reminds us that careful observation and a comprehensive approach to healthcare are essential for managing chronic conditions like ESRD.

Dr. Camel's Conclusion

The study highlights the importance of meticulous patient monitoring, even with widely prescribed medications like sevelamer. It's like keeping a watchful eye on a caravan traveling through a vast and unforgiving desert. This research serves as a reminder that unexpected complications can arise, underscoring the importance of a vigilant approach to healthcare.
Date :
  1. Date Completed n.d.
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

29682371

DOI: Digital Object Identifier

PMC5851163

SNS
PICO Info
in preparation
Languages

English

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