Vigabatrin for Epileptic Spasms and Tonic Seizures in Tuberous Sclerosis Complex.

Author: PetersJurriaan M, SahinMustafa, van der Poest ClementEmma A

Paper Details 
Original Abstract of the Article :
Vigabatrin is recommended as first-line treatment for infantile spasms in tuberous sclerosis complex (TSC), but other indications in children with tuberous sclerosis complex are less known. We retrospectively reviewed 201 children with tuberous sclerosis complex, and identified 21 children older tha...See full text at original site
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引用元:
https://doi.org/10.1177/0883073818768309

データ提供:米国国立医学図書館(NLM)

Vigabatrin: A Potential Treatment for Seizures Beyond Infancy in Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is a rare genetic disorder that can cause seizures and other health problems. This study examines the effectiveness of vigabatrin, an anticonvulsant medication, in treating seizures in children with TSC beyond infancy. The researchers retrospectively reviewed data from children with TSC who were started on vigabatrin for various seizure types, including epileptic spasms and tonic seizures.

Vigabatrin Demonstrates Effectiveness in Older Children with TSC

The study found that vigabatrin was effective in reducing seizure frequency in children with TSC, even beyond infancy. The medication was well-tolerated, with minimal side effects reported. The findings suggest that vigabatrin could be a valuable treatment option for children with TSC experiencing various seizure types.

Navigating TSC Treatment: A Comprehensive Approach

This study offers valuable information for clinicians managing seizures in children with TSC. It highlights the potential of vigabatrin as a treatment option beyond infancy, suggesting that a multidisciplinary approach incorporating medication, behavioral therapies, and ongoing monitoring may be beneficial for managing this complex condition. Think of it like this: a camel navigating a desert needs to be aware of its surroundings and adapt to changing conditions. Similarly, treating TSC requires a multifaceted approach to address the various challenges faced by individuals with this disorder.

Dr. Camel's Conclusion

This study provides valuable insights into the potential of vigabatrin in treating seizures in children with TSC beyond infancy. The findings encourage further investigation into the long-term effectiveness and safety of this medication in managing this challenging condition. Remember, a camel traversing a desert needs to be well-prepared and have access to the right resources to ensure its survival. Similarly, treating TSC requires a comprehensive approach to provide optimal care for individuals with this complex disorder.
Date :
  1. Date Completed 2019-06-18
  2. Date Revised 2019-06-18
Further Info :

Pubmed ID

29687739

DOI: Digital Object Identifier

10.1177/0883073818768309

Related Literature

SNS
PICO Info
in preparation
Languages

English

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