Paper Details

  1. Home
  2. Paper Details

Predictive Factors of Patients' and Their Partners' Sexual Function Improvement After Collagenase Clostridium Histolyticum Injection for Peyronie's Disease: Results From a Multi-Center Single-Arm Study.

Author: ArcanioloDavide, CacciamaniGiovanni, CaiTommaso, CapeceMarco, CitoGianmartin, CocciAndrea, FalconeMarco, GacciMauro, GaraffaGiulio, GiammussoBruno, GiubileiGianluca, GrecoIsabella, MinerviniAndrea, MironeVincenzo, MondainiNicola, PolloniGaia, RegisFederica, RussoGiorgio Ivan, SaloniaAndrea, TimpanoMassimiliano

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

This study evaluated the efficacy and safety of a modified collagenase Clostridium histolyticum (CCH) injection protocol for stable Peyronie's disease (PD) in a large cohort of sexually active men. The protocol resulted in significant improvement in penile curvature, erectile function, and overall satisfaction. Additionally, partners showed improved sexual function. This suggests that the modified CCH protocol can effectively improve both patient and partner sexual function in men with PD.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Collagenase Clostridium histolyticum (CCH; Xiapex) injections represent the only licensed medical treatment for Peyronie's disease (PD). AIM: To evaluate the efficacy and safety of CCH injections in men with stable PD, using a modified treatment protocol and to assess partners' bother i...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.jsxm.2018.03.084

データ提供：米国国立医学図書館（NLM）

Improving Sexual Function in Men with Peyronie's Disease

The world of medical research is always searching for new solutions, and this study tackles a very real issue faced by men: Peyronie's disease. Imagine a camel with a bent neck, unable to carry its load smoothly. This disease affects the penis in a similar way, causing curvature and pain, hindering a man's ability to perform sexually. This study looks at a specific treatment called Collagenase Clostridium histolyticum (CCH) injections. The study utilized a rigorous approach with a group of sexually active men, assessing the efficacy and safety of this injection-based treatment. The researchers discovered that the CCH injections not only improved the men's sexual function but also positively impacted their partners' sexual satisfaction.

A promising treatment for Peyronie's disease

The study found that the modified CCH treatment protocol significantly improved both patients' and partners' sexual function. The average change in penile curvature was 19.07 degrees, which is a significant improvement. It's like a camel with a bent neck slowly regaining its natural posture, allowing it to carry its burden with more ease. This research highlights the potential of CCH injections as a viable treatment option for Peyronie's disease.

The impact on relationships

This research suggests that CCH injections can have a positive impact on relationships by improving sexual function for both partners. Imagine two camels traversing the desert together, their movements coordinated and fluid. A healthy sexual relationship is crucial for a couple's well-being, and this study highlights the importance of finding effective treatments for conditions that can affect sexual function.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of CCH injections in treating Peyronie's disease. This research suggests that CCH injections are a promising treatment option for men with this condition, and it highlights the importance of considering the impact of such treatments on both partners.

Date :
  1. Date Completed 2019-11-01
  2. Date Revised 2019-11-01
Further Info :

Pubmed ID

29699756

DOI: Digital Object Identifier

10.1016/j.jsxm.2018.03.084

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.