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Drug-drug interactions in the treatment for alcohol use disorders: A comprehensive review.

Author: CaputoFabio, GuerzoniSimona, PellesiLanfranco, PiniLuigi Alberto

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review focuses on drug interactions in patients with alcohol use disorder (AUD). While benzodiazepines and disulfiram have numerous interactions, acamprosate is relatively safe. Other medications like nalmefene and naltrexone can cause opioid withdrawal syndrome when combined with opioids. This information helps clinicians understand and manage drug interactions in AUD patients, particularly those on multiple medications, to improve treatment outcomes and reduce adverse effects.
Paper Details　
Original Abstract of the Article :
Drug interactions are one of the most common causes of side effects in polypharmacy. Alcoholics are a category of patients at high risk of pharmacological interactions, due to the presence of comorbidities, the concomitant intake of several medications and the pharmacokinetic and pharmacodynamic int...See full text at original site
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引用元：
https://doi.org/10.1016/j.phrs.2018.04.024

データ提供：米国国立医学図書館（NLM）

Navigating Drug Interactions: A Guide for Treating Alcohol Use Disorders

The field of alcohol use disorder (AUD) treatment is a complex desert, with researchers seeking to develop effective therapies while navigating the complexities of drug interactions. This study examines the potential drug interactions associated with various medications used for AUD treatment. It's like exploring a desert landscape dotted with hidden oases, each one representing a different medication with its own unique properties and risks. The authors are providing a comprehensive review of drug interactions, hoping to guide clinicians in safely prescribing medications for AUD.

A Delicate Balance: Understanding Drug Interactions

The study reveals that certain medications commonly used for AUD treatment, such as benzodiazepines and disulfiram, have a high risk of drug interactions. It's like navigating a treacherous desert path, where unexpected dangers can arise. This emphasizes the need for careful monitoring and management of drug interactions in patients with AUD, ensuring their safety and well-being.

Improving Treatment Outcomes: A Multi-Disciplinary Approach

This research highlights the importance of a multi-disciplinary approach to AUD treatment, considering not only the medications but also the individual patient's characteristics and potential drug interactions. It's like a team of camels working together to navigate a challenging desert journey, each one contributing its expertise. By carefully evaluating potential interactions, clinicians can optimize treatment outcomes and minimize risks for individuals with AUD.

Dr.Camel's Conclusion

This study offers a valuable guide for navigating the complex world of drug interactions in AUD treatment. Like a camel using its knowledge of the desert to avoid hidden dangers, clinicians must carefully consider the potential risks and benefits of different medications. By collaborating with patients and other healthcare professionals, we can work together to create a more effective and safer approach to AUD treatment.

Date :
  1. Date Completed 2019-02-26
  2. Date Revised 2019-02-26
Further Info :

Pubmed ID

29719204

DOI: Digital Object Identifier

10.1016/j.phrs.2018.04.024

SNS
PICO Info
in preparation
Languages

English

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