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High-dose vitamin D3 in the treatment of severe acute malnutrition: a multicenter double-blind randomized controlled trial.

Author: BelayMulugeta, MartineauAdrian R, RoweMarion, SaleemJaveria, ScraggRobert, TimmsPeter M, ZakarMuhammad Z, ZakarRubeena

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

High-dose vitamin D3 supplementation improved weight-for-height or -length z score and reduced delayed developmental indexes in children with uncomplicated severe acute malnutrition in Pakistan. However, it did not influence the proportion of children gaining >15% of baseline weight.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Vitamin D deficiency is common in children with severe acute malnutrition, in whom it is associated with severe wasting. Ready-to-use therapeutic food (the standard treatment) contains modest amounts of vitamin D that do not reliably correct deficiency. OBJECTIVE: The aim of this study ...See full text at original site
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引用元：
https://doi.org/10.1093/ajcn/nqy027

データ提供：米国国立医学図書館（NLM）

Vitamin D and Malnutrition: A Camel's Sun-Kissed Journey to Health

This research investigates the role of vitamin D supplementation in children suffering from severe acute malnutrition. Imagine a camel, weakened by hunger and dehydration, struggling to survive in the harsh desert environment. This study explores how high-dose vitamin D3 could help these children regain their strength and vitality.

Vitamin D: A Sun-Kissed Remedy for Malnutrition

The study found that high-dose vitamin D3 supplementation, in addition to standard treatment, significantly improved the mean weight-for-height or length z-score and developmental indexes in children with uncomplicated severe acute malnutrition. It's like providing a camel with a source of essential nutrients, helping it regain its strength and energy, enabling it to navigate the desert landscape with renewed vigor. The study demonstrates the crucial role of vitamin D in overall health and development.

Nourishing Our Young: A Camel's Legacy of Health

This research highlights the importance of addressing vitamin D deficiency, particularly in children with severe acute malnutrition. It underscores the need for adequate vitamin D intake, either through diet or supplementation, to ensure optimal growth and development. It's like ensuring a camel has access to the sun and essential nutrients, enabling it to grow strong and thrive in the challenging desert environment.

Dr.Camel's Conclusion

This study provides compelling evidence for the benefits of high-dose vitamin D3 supplementation in children with severe acute malnutrition. It underscores the importance of vitamin D for optimal growth and development, particularly in vulnerable populations.

Date :
  1. Date Completed 2019-07-04
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

29722846

DOI: Digital Object Identifier

10.1093/ajcn/nqy027

Related Literature

Article Analysis
・Effective treatment of vitamin d deficiency
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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