Anti-glioma Effects of Caffeic Acid Phenethyl Ester and Dasatinib Combination Therapy in an in vivo Rat Glioma Model.

Author: BalkhiHenah Mehraj, GulTaseen, HaqEhtishamul, SanaSyed

Paper Details 
Original Abstract of the Article :
BACKGROUND: Caffeic acid phenethyl ester and Dasatinib in combination, when used incongruous proportions and durations, present an antitumor potential for glioma in vitro, suggesting a high therapeutic potential for glioma treatment. OBJECTIVE: In the present study, we addressed the question whethe...See full text at original site
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引用元:
https://doi.org/10.2174/1871520618666180515144835

データ提供:米国国立医学図書館(NLM)

A Collaborative Approach to Glioma: A Tale of Two Drugs

The battle against glioma, a type of brain tumor, is a challenging journey through a dense and complex desert. This research explores the potential of a collaborative approach, like a team of explorers, to tackle this formidable foe. The study investigates the combined effects of caffeic acid phenethyl ester (CAPE) and Dasatinib, two drugs with known anti-tumor properties, on glioma cells in a rat model. The researchers aim to understand whether these two drugs, working together, can effectively combat the growth and spread of glioma.

A Dynamic Duo in the Fight Against Glioma

The study found that CAPE and Dasatinib, when used together, effectively reduced the proliferation of glioma cells in the rat model. The combination therapy, like a well-coordinated team, targeted multiple pathways involved in tumor growth and development, potentially leading to more effective tumor control. This research suggests that the combination of these two drugs may offer a promising strategy for managing gliomas, potentially overcoming the limitations of single-drug therapy.

A Beacon of Hope in the Glioma Desert

This study offers a ray of hope in the desert of glioma research. The findings suggest that a collaborative approach, utilizing multiple drugs that target different aspects of tumor growth, may hold the key to more effective treatment strategies. While more research is needed to validate these findings in human trials, this study provides valuable insights into the potential of combination therapy for managing gliomas.

Dr.Camel's Conclusion

This study provides a promising roadmap through the challenging desert of glioma treatment. The combination of CAPE and Dasatinib, like a dynamic duo, offers a collaborative approach to combatting this formidable foe. This research holds the potential to revolutionize glioma treatment, offering new hope for patients facing this devastating disease.

Date :
  1. Date Completed 2019-07-17
  2. Date Revised 2019-07-17
Further Info :

Pubmed ID

29766825

DOI: Digital Object Identifier

10.2174/1871520618666180515144835

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Languages

English

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