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Targeted therapies and adverse drug reactions in oncology: the role of clinical pharmacist in pharmacovigilance.

Author: AlibertiM, BaldoP, De PaoliP, FornasierG, FrancesconS, PoleselJ, TaborelliM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

This observational study analyzed adverse drug reactions (ADRs) in a real-world setting. The reported ADRs did not always correspond with the data described in the respective summaries of product characteristics (SPCs). Unknown ADRs were identified. The study also observed a significant increase in spontaneous reports. These findings highlight the importance of active pharmacovigilance programs and suggest the need for further investigation.
Paper Details　
Original Abstract of the Article :
Background The majority of adverse drug reactions (ADRs) reported in the summary of product characteristics (SPCs) are based on pivotal clinical trials, performed under controlled conditions and with selected patients. Objectives (1) to observe ADRs in the real-world setting and to evaluate if the s...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132980/

データ提供：米国国立医学図書館（NLM）

The Crucial Role of Clinical Pharmacists in Pharmacovigilance

Targeted therapies, a promising approach to cancer treatment, are often associated with unique side effects. This study explores the role of clinical pharmacists in pharmacovigilance, the process of monitoring the safety of drugs, specifically in the context of targeted therapies for oncology. Think of it as a team of desert explorers, carefully charting the terrain of targeted therapies, ensuring the safety and well-being of those seeking treatment.

The study highlights the importance of active pharmacovigilance programs in identifying and managing adverse drug reactions associated with targeted therapies. The study found that adverse drug reactions observed in real-world settings may differ from those reported in clinical trials. The study also emphasizes the valuable contribution of clinical pharmacists in enhancing patient satisfaction and promoting the reporting of adverse drug reactions.

Pharmacovigilance: A Key Element in Safe and Effective Cancer Treatment

This research underscores the critical importance of pharmacovigilance in ensuring the safe and effective use of targeted therapies in cancer treatment. It's like having a team of desert guides, carefully monitoring the terrain, ensuring the safety of those seeking treatment.

Navigating the Complexities of Cancer Treatment

Cancer treatment involves a complex interplay of medications, side effects, and individual patient characteristics. This study emphasizes the vital role of clinical pharmacists in navigating this complex landscape, ensuring the safety and well-being of patients undergoing cancer treatment.

Dr. Camel's Conclusion

This research sheds light on the crucial role of clinical pharmacists in pharmacovigilance, highlighting their importance in ensuring the safe and effective use of targeted therapies for cancer treatment. It's like a beacon of hope in the desert, guiding us towards a safer and more effective journey for those battling cancer.

Date :
  1. Date Completed 2018-12-11
  2. Date Revised 2021-02-16
Further Info :

Pubmed ID

29785683

DOI: Digital Object Identifier

PMC6132980

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Languages

English

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