A retrospective study evaluating the tolerability and effectiveness of adjunctive antihypertensive drugs in patients with inadequate response to initial treatment.

Author: AyyagariRajeev, ChenStephanie, ChengDavid, HuangXing-Yue, WuEric Q, XieJipan

Paper Details 
Original Abstract of the Article :
Real-world tolerability and effectiveness of nebivolol as first add-on therapy were compared with hydrochlorothiazide, metoprolol, and amlodipine. Medical records of hypertensive adults initiating nebivolol, hydrochlorothiazide, metoprolol, or amlodipine as first add-on therapy between December 16, ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033036/

データ提供:米国国立医学図書館(NLM)

Evaluating Adjunctive Antihypertensive Drugs

High blood pressure, or hypertension, is a common condition that requires careful management. This study examines the tolerability and effectiveness of different adjunctive antihypertensive drugs in patients who did not adequately respond to initial treatment. Think of it as exploring different strategies for navigating a desert landscape, seeking the most effective path to lower blood pressure.

Nebivolol Shows Promise as First Add-on Therapy

The study found that nebivolol, as a first add-on therapy, was associated with fewer side effects compared to other drugs like metoprolol and amlodipine. It also resulted in a higher blood pressure control rate. It's like finding a smoother and more pleasant route through the desert, leading to a better outcome.

Optimizing Blood Pressure Management

This research emphasizes the importance of considering individual patient needs when selecting adjunctive antihypertensive drugs. The findings suggest that nebivolol might be a valuable option for patients who experience side effects from other medications. It's like finding a more suitable camel for a particular journey – ensuring comfort and efficiency.

Dr. Camel's Conclusion

This study highlights the importance of tailoring antihypertensive therapy to individual patient needs. It emphasizes the value of considering both tolerability and effectiveness when selecting adjunctive drugs, ultimately improving the overall management of hypertension.

Date :
  1. Date Completed 2019-11-27
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

29902367

DOI: Digital Object Identifier

PMC6033036

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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