Clinically relevant drug-drug interactions among elderly people with dementia.

Author: GustafssonMaria, LövheimHugo, SjölanderMaria, SönnerstamEva

Paper Details 
Original Abstract of the Article :
Increased numbers of drugs and changes in pharmacokinetic and pharmacodynamic parameters among elderly people contribute to increased prevalence of adverse drug reactions. Drug-drug interactions (DDIs) are an important reason for admission to hospital and elderly people with dementia are particularl...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132551/

データ提供:米国国立医学図書館(NLM)

Drug-Drug Interactions in Elderly People with Dementia: Navigating a Complex Desert

This study investigates the prevalence and characteristics of clinically relevant drug-drug interactions (DDIs) in elderly people with dementia. The authors highlight the increased vulnerability of this population to DDIs due to polypharmacy and changes in pharmacokinetic and pharmacodynamic parameters. The research examines the occurrence and potential risk factors associated with DDIs, emphasizing the importance of careful medication management and minimizing the use of potentially problematic drugs. The study underscores the need for vigilance in monitoring and managing medication regimens for elderly patients with dementia to prevent adverse drug events.

Drug-Drug Interactions: A Challenging Desert Landscape

The study reveals the significant challenges associated with managing medication regimens for elderly people with dementia, particularly the increased risk of DDIs. The research highlights the importance of careful medication selection, minimizing polypharmacy, and close monitoring of patients for potential drug interactions. The findings emphasize the need for a comprehensive approach to medication management for this vulnerable population.

Navigating the Desert of Polypharmacy

The desert of polypharmacy can be a treacherous landscape for elderly people with dementia, increasing the risk of adverse drug events. This study underscores the importance of careful medication management, minimizing the use of potentially problematic drugs, and closely monitoring patients for potential DDIs. The findings emphasize the need for a collaborative approach among healthcare professionals, pharmacists, and patients to ensure safe and effective medication regimens for elderly patients with dementia.

Dr.Camel's Conclusion

The desert of polypharmacy can be a challenging environment for elderly people with dementia, increasing the risk of DDIs. This study highlights the importance of careful medication management, minimizing polypharmacy, and closely monitoring patients for potential drug interactions to navigate this landscape safely and effectively.

Date :
  1. Date Completed 2018-12-19
  2. Date Revised 2018-12-19
Further Info :

Pubmed ID

29967921

DOI: Digital Object Identifier

PMC6132551

Related Literature

SNS
PICO Info
in preparation
Languages

English

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