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Successful Treatment of Severe Atopic Dermatitis with Calcitriol and Paricalcitol in an 8-Year-Old Girl.

Author: AlexopoulosAlexis, BothouChristina, DermitzakiEleni, KleanthousKleanthis, MastorakosGeorge, PapadimitriouAnastasios, PapadimitriouDimitrios T

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This report describes a case of a girl with severe atopic dermatitis (AD) who achieved significant improvement with calcitriol therapy, followed by paricalcitol due to hypercalciuria. Calcitriol and paricalcitol may be considered safe and effective treatment options for severe AD, particularly for those with refractory disease.
Paper Details　
Original Abstract of the Article :
Atopic dermatitis (AD) is a chronic inflammatory disease affecting children and adolescence. The traditional therapeutic options for AD, including emollients topically and immune modulatory agents systemically focusing on reducing skin inflammation and restoring the function of the epidermal barrier...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035840/

データ提供：米国国立医学図書館（NLM）

Calcitriol and Paricalcitol: A New Path for Atopic Dermatitis

Atopic dermatitis (AD), a chronic inflammatory skin disease, can significantly impact an individual's quality of life. This study presents a case report of an 8-year-old girl with severe AD who experienced significant improvement in her symptoms after treatment with calcitriol and paricalcitol, vitamin D analogs. The researchers investigated the potential of these vitamin D analogs as therapeutic agents for AD.

Calcitriol and Paricalcitol: A Potential Treatment for Severe Atopic Dermatitis

The study reported a remarkable response to calcitriol therapy in the 8-year-old patient with severe AD. Her skin lesions showed significant improvement, nearly complete healing, within two months. This improvement was sustained for more than three years, demonstrating the potential long-term benefits of calcitriol therapy.

Hope for Atopic Dermatitis: Exploring New Treatment Options

This case report, although limited, offers hope for individuals with severe AD, particularly those who have not responded to traditional therapies. The findings suggest that calcitriol and paricalcitol could provide an alternative treatment approach for this challenging condition. However, further research is needed to validate these findings and explore the broader applicability of vitamin D analogs in the management of AD.

Dr.Camel's Conclusion

This study highlights the potential of vitamin D analogs, calcitriol and paricalcitol, in managing severe AD. The case report provides a promising glimpse into the potential of these agents as therapeutic options. Further research is essential to validate these findings and explore their safety and efficacy in a broader population.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

30034905

DOI: Digital Object Identifier

PMC6035840

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Article Analysis
・Side Effects of calcitriol topical
SNS
PICO Info
in preparation
Languages

English

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