Higher Neural Correlates in Patients with Multiple Sclerosis and Neurogenic Overactive Bladder Following Treatment with Intradetrusor Injection of OnabotulinumtoxinA.

Author: BooneTimothy B, EliasSaba N, KarmonikChristof, KhavariRose, PandeRashmi, WuKatherine M

Paper Details 
Original Abstract of the Article :
OnabotulinumtoxinA is a well described treatment of neurogenic overactive bladder. While motor effects on the detrusor muscle have been extensively studied, the sensory effects have not. The aim of this study was to evaluate the impact of intradetrusor onabotulinumtoxinA injection on brain activity ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/30076906

データ提供:米国国立医学図書館(NLM)

OnabotulinumtoxinA: A Promising Treatment for Neurogenic Overactive Bladder in Multiple Sclerosis

This research investigates the effectiveness of [onabotulinumtoxinA] injections for treating [neurogenic overactive bladder] in patients with [multiple sclerosis (MS)]. The study explores the impact of [onabotulinumtoxinA] on brain activity, specifically the [neural correlates] associated with [bladder control]. The findings suggest that [onabotulinumtoxinA] may not only improve bladder function but also influence brain activity, providing valuable insights into the neurological mechanisms underlying [neurogenic overactive bladder] in [MS].

OnabotulinumtoxinA: A Potential Game Changer for Bladder Control

The study found that [onabotulinumtoxinA] injections led to a significant increase in neural activity in areas of the brain associated with [bladder control]. This suggests that [onabotulinumtoxinA] may not only improve bladder function but also influence brain activity, potentially leading to a more comprehensive understanding of the neurological mechanisms underlying [neurogenic overactive bladder] in [MS]. This is a significant finding that could pave the way for more effective treatment strategies for this challenging condition.

Navigating the Desert of Bladder Control: Finding a Path to Relief

This research offers hope for patients with [neurogenic overactive bladder] due to [MS]. The findings suggest that [onabotulinumtoxinA] may provide a more effective and long-lasting solution for managing this condition. It's like finding a refreshing oasis in a vast, dry desert – a source of relief and comfort for those struggling with bladder control issues. This research encourages further exploration of [onabotulinumtoxinA] as a promising therapeutic option for [neurogenic overactive bladder] in [MS].

Dr.Camel's Conclusion

This study demonstrates the potential of onabotulinumtoxinA for treating neurogenic overactive bladder in patients with multiple sclerosis. The findings suggest that onabotulinumtoxinA not only improves bladder function but also influences brain activity, potentially offering a more comprehensive approach to managing this challenging condition. This research encourages further exploration of onabotulinumtoxinA as a promising therapeutic option for patients seeking relief from neurogenic overactive bladder.

Date :
  1. Date Completed 2019-03-18
  2. Date Revised 2020-03-09
Further Info :

Pubmed ID

30076906

DOI: Digital Object Identifier

NIHMS988865

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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