Paper Details

  1. Home
  2. Paper Details

Toxicity of tapentadol: a systematic review.

Author: ChannellJessie S, SchugStephan

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Tapentadol use, whether prescribed or abused, has been associated with mortality and serious adverse events including respiratory depression, confusion, coma, hallucination, seizures, tachycardia, hypertension, agitation, tremor, miosis, hypotension, dyspnea, electrolyte abnormality, atrial fibrillation, and severe upper abdominal pain.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Tapentadol is a novel atypical opioid. Anecdotal evidence suggests that tapentadol has a lower toxicity than conventional opioids. OBJECTIVES: To evaluate all single-drug mortality due to tapentadol and assess serious adverse events caused by tapentadol. METHODS: The Preferred Reportin...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.2217/pmt-2018-0027

データ提供：米国国立医学図書館（NLM）

Tapentadol: A Look at Its Toxicity

[Tapentadol] is a novel atypical opioid that has emerged as a potential treatment option for pain. However, it's important to understand the potential risks associated with any medication, including tapentadol. This study, like a cautious traveler in a desert, investigates the toxicity of tapentadol.

Navigating the Risks of Tapentadol

The researchers found that tapentadol can cause mortality and serious adverse effects. This highlights the importance of careful monitoring and appropriate use of this medication. The study also found that tapentadol's toxicity is significantly less than pure mu opioids, such as oxycodone. This finding is like discovering a hidden oasis in a harsh desert, providing a sense of hope and relief.

Understanding the Risks and Benefits

It's crucial to weigh the potential risks and benefits of any medication, including tapentadol. While this medication can offer relief from pain, it's essential to be aware of its potential side effects and to work closely with a healthcare provider to determine the appropriate course of treatment. This is like carefully navigating a desert, where understanding the terrain and its hazards is essential for a safe and successful journey.

Dr.Camel's Conclusion

This study provides important information about the toxicity of tapentadol. It's crucial to use this medication responsibly and to be aware of its potential risks. By understanding the potential hazards and working closely with healthcare professionals, we can navigate the challenges of managing pain with greater confidence and well-being.

Date :
  1. Date Completed 2018-11-26
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

30079795

DOI: Digital Object Identifier

10.2217/pmt-2018-0027

Related Literature

Article Analysis
・Side Effects of tapentadol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.