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Comparable efficacy and less toxicity of pegylated liposomal doxorubicin versus epirubicin for neoadjuvant chemotherapy of breast cancer: a case-control study.
Author: DongMinjun, JiangZhinong, LuXianqiu, LuoLiang, ShenJianguo, WangLinbo, YingXiaogang
Original Abstract of the Article :
Pegylated liposomal doxorubicin (PLD) and epirubicin are both superior variants of doxorubicin and are commonly applied as basic chemotherapeutics in breast cancer. However, the direct comparison of their efficacy and side effects has not been adequately reported. This study aimed to compare the eff...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061676/
データ提供:米国国立医学図書館(NLM)
Weighing the Options: Pegylated Liposomal Doxorubicin vs. Epirubicin in Neoadjuvant Chemotherapy
The [treatment of breast cancer] often involves [chemotherapy] to shrink tumors before surgery. This research, like a careful chemist blending different ingredients, compares the effectiveness and side effects of two [chemotherapy drugs]: [pegylated liposomal doxorubicin (PLD)] and [epirubicin]. The researchers conducted a [case-control study] to assess the relative efficacy and toxicity of these drugs when used as [neoadjuvant chemotherapy] for [invasive breast cancer].
Balancing the Scales: Comparing the Efficacy and Toxicity of PLD and Epirubicin
The study reveals that both [PLD] and [epirubicin] demonstrated [comparable efficacy] in [neoadjuvant chemotherapy] for [breast cancer]. However, the researchers observed that [PLD] was associated with [less toxicity] compared to [epirubicin].
Navigating the Desert of Breast Cancer Treatment: Choosing the Right Path
This research offers valuable insights for [oncologists] treating [breast cancer]. The findings suggest that [PLD] may be a more tolerable option for [neoadjuvant chemotherapy] while maintaining [comparable efficacy]. By carefully considering the potential benefits and risks of different chemotherapy drugs, oncologists can make informed decisions that best suit the needs of their patients.
Dr.Camel's Conclusion
The desert of breast cancer treatment can be a challenging and uncertain landscape. This research sheds light on the comparative efficacy and toxicity of two common chemotherapy drugs, providing valuable information for oncologists and patients alike. By understanding the nuances of these treatment options, we can navigate this complex terrain with greater confidence and strive for optimal outcomes.
Date :
- Date Completed n.d.
- Date Revised 2022-04-09
Further Info :
Related Literature
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