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Ferritin level changes and erythroid improvement in a group of adult polytransfused patients treated with Deferasirox.
Author: BojanAnca, IancuMihaela, ParvuAndrada Viorica, TorokTunde, UrianLaura, ZsoldosIulia Andrea
Original Abstract of the Article :
Chelating agents therapy is recommended for polytransfused patients that have evidence of iron overload (an elevated serum ferritin or received over 20 units of red blood cell transfusions). Deferasirox showed efficacy and safety in maintaining or reducing body iron. Iron chelation therapy was assoc...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082613/
データ提供:米国国立医学図書館(NLM)
Deferasirox: A Camel in the Desert of Iron Overload
The desert of iron overload is a challenging landscape, with the accumulation of excess iron posing significant risks to health. This study examines the efficacy of deferasirox, an iron chelating agent, in managing iron overload in adult polytransfused patients. The authors investigated the impact of deferasirox on ferritin levels, a marker of iron overload, and assessed its ability to improve erythroid parameters and reduce the need for red blood cell transfusions.
Deferasirox: A Oasis in the Desert of Iron Overload
The authors found that deferasirox effectively reduced ferritin levels in adult polytransfused patients, indicating its ability to control iron overload. They also observed improvement in erythroid parameters and a reduction in the number of red blood cell transfusions after the introduction of deferasirox. These findings suggest that deferasirox is a valuable tool for managing iron overload in this patient population.
A Journey Through the Desert of Iron Overload: The Importance of Chelation Therapy
The journey through the desert of iron overload is often a long and challenging one. This study highlights the importance of iron chelation therapy, using agents like deferasirox, to manage iron overload and prevent its associated complications. By effectively removing excess iron from the body, chelation therapy can help individuals navigate this desert and improve their overall health and well-being.
Dr. Camel's Conclusion
The desert of iron overload can be a harsh and unforgiving place, but deferasirox offers a promising oasis for those seeking relief. This study demonstrates its effectiveness in managing iron overload and improving erythroid parameters in polytransfused patients. The journey through this desert requires vigilance and proper management, with chelation therapy playing a crucial role in preventing the devastating consequences of iron overload.
Date :
- Date Completed n.d.
- Date Revised 2022-03-18
Further Info :
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