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A non-comparative study of parenteral ampicillin and sulbactam in intra-thoracic and intra-abdominal infections.

Author: CroftR J, HilasA, MehtarS

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Intravenous ampicillin and sulbactam effectively treated intra-thoracic and intra-abdominal infections in 54 patients. The combination resulted in clinical and bacteriological response in a high percentage of patients with severe respiratory tract or intra-abdominal infections. Minimal side effects were observed, with pain at the injection site being the most common.
Paper Details　
Original Abstract of the Article :
Fifty-four patients were treated with intravenous ampicillin and sulbactam in an open study of intra-thoracic and intra-abdominal infection. Thirty-one were treated with 500 mg each of the combination 6-hourly while 23 patients were given 1 g of ampicillin and 500 mg of sulbactam, 6-hourly. Thirteen...See full text at original site
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引用元：
https://doi.org/10.1093/jac/17.3.389

データ提供：米国国立医学図書館（NLM）

Ampicillin and Sulbactam: A Powerful Duo in the Desert of Infections

This research delves into the realm of antibiotic therapy, focusing on the effectiveness of a combination of ampicillin and sulbactam in treating intra-thoracic and intra-abdominal infections. Think of it as a team of explorers venturing into the desert of infection, armed with a potent weapon against the microbial invaders. The study analyzed the clinical and bacteriological responses of 54 patients with these infections who were treated with intravenous ampicillin and sulbactam.

A Winning Combination: A Powerful Alliance in the Desert

The study found that the combination of ampicillin and sulbactam was effective in treating a majority of patients with severe respiratory tract infections and intra-abdominal infections. This combination demonstrated a high rate of clinical and bacteriological response, indicating its effectiveness in combating these challenging infections.

Navigating the Desert of Infections: A Targeted Approach

This research highlights the importance of targeted antibiotic therapy, where appropriate combinations of drugs can be crucial for achieving optimal results. The study's findings support the use of ampicillin and sulbactam as a viable treatment option for specific types of infections.

Dr.Camel's Conclusion

This study is like a well-stocked oasis in the desert of infection, showcasing the effectiveness of ampicillin and sulbactam in combatting challenging infections. The research underscores the importance of targeted antibiotic therapy and the potential for this combination to provide a valuable tool for treating specific types of infections.

Date :
  1. Date Completed 1986-06-06
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

3009384

DOI: Digital Object Identifier

10.1093/jac/17.3.389

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・Side Effects of ampicillin injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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