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Gefitinib successfully administered in a lung cancer patient with leptomeningeal carcinomatosis after erlotinib-induced pneumatosis intestinalis.
Author: HanadaShigeo, KishiKazuma, MiyamotoAtsushi, MochizukiSayaka, MoriguchiShuhei, MorokawaNasa, MuraseKyoko, OgawaKazumasa, TakahashiYui, TakayaHisashi, UrugaHironori
Original Abstract of the Article :
BACKGROUND: Pneumatosis intestinalis (PI) is a rare complication of chemotherapy, characterized by multiple gas accumulations within the bowel wall. CASE PRESENTATION: A 71-year-old woman with epidermal growth factor receptor (EGFR) mutation-positive lung adenocarcinoma was admitted to our hospital...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097412/
データ提供:米国国立医学図書館(NLM)
Gefitinib: A Potential Alternative for Lung Cancer Treatment
In the complex world of cancer treatment, finding the right medication for each patient is like searching for a specific oasis in a vast desert. This case study focuses on a patient with lung cancer who experienced a rare side effect from a common treatment. The researchers explored alternative options to ensure the patient received the best care possible.
The patient had lung cancer with a specific genetic mutation, making them a prime candidate for targeted therapy. The researchers initially prescribed erlotinib, a medication that specifically targets this mutation. Unfortunately, the patient developed a serious side effect called pneumatosis intestinalis, characterized by gas buildup in the intestinal wall. This is like a balloon accidentally inflating inside your digestive system!
Gefitinib Offers Hope for Patients with Lung Cancer
The researchers switched the patient to gefitinib, a similar medication, and thankfully, the side effects disappeared. The patient continued to receive treatment with gefitinib and lived for an additional 8 months. This case study highlights the importance of carefully monitoring patients for side effects and the value of exploring alternative treatment options when necessary.
Finding the Right Treatment for Lung Cancer: A Balancing Act
This research serves as a reminder that finding the right treatment for lung cancer is a delicate dance between efficacy and side effects. It is important to understand the potential benefits and risks of different medications and to work closely with doctors to make informed decisions.
Dr.Camel's Conclusion
This case study is a testament to the resilience of the human spirit and the power of medical innovation. It demonstrates that even in the face of adversity, there may be alternative pathways to better health. This is a valuable lesson for both patients and medical professionals alike, emphasizing the importance of open communication, careful monitoring, and the unwavering pursuit of better treatments.
Date :
- Date Completed 2018-10-29
- Date Revised 2018-12-02
Further Info :
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