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Lidocaine/Phenylephrine Nasal Spray versus Nebulization Prior to Nasoendoscopy: A Randomized Controlled Trial.

Author: ArvinBalachandran, GohLiang Chye, PrepageranNarayanan, ZulkifleeAbu Bakar

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effectiveness of two ways to deliver a nasal spray containing lidocaine and phenylephrine. The spray was either delivered through a nebulizer or as a regular nasal spray. The study found that the nebulizer delivered the medicine more effectively, reducing nasal congestion and pain more quickly.
Paper Details　
Original Abstract of the Article :
Objective To objectively compare the nasal decongestion potency of lidocaine/phenylephrine when delivered with a nasal nebulizer and a nasal spray before a rigid nasoendoscopic examination. Study Design Open-label randomized controlled trial. Setting Multicenter study. Methods This prospective clini...See full text at original site
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引用元：
https://doi.org/10.1177/0194599818795852

データ提供：米国国立医学図書館（NLM）

Nasal Decongestion: Comparing Spray and Nebulization

Nasal congestion is a common symptom affecting breathing and overall comfort. This study compares the effectiveness of lidocaine/phenylephrine, a common nasal decongestant, when delivered via a nasal nebulizer versus a nasal spray. The research involved a randomized controlled trial comparing the two methods in individuals with chronic rhinitis.

Nebulization: A More Effective Approach to Nasal Decongestion

The study found that nebulization of lidocaine/phenylephrine provided superior nasal decongestion compared to nasal spray administration. Nebulization resulted in a more significant reduction in nasal resistance and a better subjective assessment of nasal decongestion. Additionally, nebulization was associated with less pain when applying pressure to the inferior turbinate.

Optimizing Nasal Decongestion

This research suggests that nebulization may be a more effective method for delivering lidocaine/phenylephrine for nasal decongestion. The study highlights the importance of considering different delivery methods to optimize treatment outcomes and patient comfort.

Dr. Camel's Conclusion

Imagine a desert oasis, where a gentle breeze carries the scent of cool water. Nasal congestion, like a desert sandstorm, can make breathing difficult. Nebulization, like a refreshing breeze, offers a more effective and comfortable way to clear nasal congestion. This study highlights the importance of considering different delivery methods to achieve optimal treatment outcomes and improve patient comfort.

Date :
  1. Date Completed 2019-09-26
  2. Date Revised 2019-09-26
Further Info :

Pubmed ID

30126325

DOI: Digital Object Identifier

10.1177/0194599818795852

Related Literature

Article Analysis
・Effects of phenylephrine nasal spray
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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