Treatment of Myasthenia Gravis With High-Dose Cholinesterase Inhibitors and Calcineurin Inhibitors Caused Spontaneous Muscle Cramps in Patients.

Author: AizawaHitoshi, HiranoToshihiko, MaenoAkemi, MasudaMasayuki, SugiyamaKentaro, TanakaSachiko, UtsumiHiroya, YamamotoMamiko

Paper Details 
Original Abstract of the Article :
OBJECTIVES: The objective of this study was to investigate the influence of treatment with cholinesterase inhibitors (ChEIs) and calcineurin inhibitors (CNIs) on the occurrence of cramps in myasthenia gravis (MG) patients. METHODS: The frequency and duration of cramp and serum electrolytes were eva...See full text at original site
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引用元:
https://doi.org/10.1097/WNF.0000000000000295

データ提供:米国国立医学図書館(NLM)

Muscle Cramps: A Side Effect of Myasthenia Gravis Treatment?

Myasthenia gravis, a rare autoimmune disorder, can be a frustrating journey through the desert of muscle weakness. This research explores the potential side effects of common treatments for myasthenia gravis, specifically focusing on muscle cramps. It's like navigating a desert landscape where unexpected obstacles and side effects can arise.

Muscle Cramps: A Desert Oasis with a Catch

The study found that muscle cramps were a common side effect in patients with myasthenia gravis, particularly those treated with high doses of cholinesterase inhibitors (ChEIs) and calcineurin inhibitors (CNIs). It's like finding an oasis that provides relief from muscle weakness but also presents a challenge in the form of muscle cramps. The study also noted that lower serum magnesium levels were associated with muscle cramps, highlighting the potential role of magnesium in preventing this side effect.

Navigating the Desert: Muscle Cramp Awareness

This research suggests that muscle cramps can be a potential side effect of certain myasthenia gravis treatments. It's like stumbling upon a patch of thorny bushes while searching for an oasis. It's important to be aware of this potential side effect and consult with your doctor to manage it effectively. Regular monitoring of magnesium levels and adjusting medication dosages could be crucial for preventing muscle cramps and ensuring a smoother journey through the desert of myasthenia gravis.

Dr.Camel's Conclusion

This research provides valuable insights into the potential side effects of myasthenia gravis treatments, highlighting the importance of monitoring muscle cramps and magnesium levels. It's like understanding the potential hazards of a desert oasis, allowing us to navigate the landscape safely and effectively. This knowledge empowers us to find solutions and enjoy the benefits of treatment without succumbing to the unexpected challenges of the journey.

Date :
  1. Date Completed 2018-12-11
  2. Date Revised 2018-12-11
Further Info :

Pubmed ID

30130259

DOI: Digital Object Identifier

10.1097/WNF.0000000000000295

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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