NEW STRATEGIES TO PREDICT AND PREVENT SERIOUS IMMUNOLOGICALLY MEDIATED ADVERSE DRUG REACTIONS.

Author: PhillipsElizabeth J

Paper Details 
Original Abstract of the Article :
Preventive efforts for serious immunologically mediated adverse drug reactions (IM-ADRs) have been fueled by discovery of strong class I human leukocyte antigen (HLA) associations; however, the low positive predictive value of HLA for IM-ADRs has limited translation. Studies were undertaken to expla...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116582/

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Adverse Drug Reactions: Unveiling the Secrets of Immune Response

In the vast and complex desert of drug development, we strive to create medications that are both effective and safe. However, adverse drug reactions, particularly those mediated by the immune system, pose significant challenges. This review explores the intricate landscape of immunologically mediated adverse drug reactions (IM-ADRs), highlighting the need for new strategies to predict and prevent these potentially life-threatening events. It's like carefully studying a map of a treacherous desert, seeking to identify and avoid the dangers that lie ahead.

A Hidden Oasis of Knowledge: Understanding the Molecular and Cellular Signatures of IM-ADRs

This review underscores the importance of understanding the molecular and cellular signatures of IM-ADRs. By delving into the intricate details of the immune response, researchers are developing new methods to identify individuals at risk of developing IM-ADRs and prevent these adverse events. It's like uncovering a hidden oasis of knowledge in the vast desert of drug development, revealing new insights into the mechanisms of immune response and paving the way for safer and more effective medications.

A Safer Desert: New Strategies to Predict and Prevent IM-ADRs

This review highlights the need for new strategies to predict and prevent IM-ADRs. By identifying individuals at risk and developing personalized treatment strategies, researchers are working to create a safer environment for drug development and patient care. It's like creating a safer path through the desert, minimizing the risk of encountering dangerous sandstorms and navigating the terrain with greater confidence. This research is a crucial step in our quest to develop safer and more effective medications for all.

Dr. Camel's Conclusion

This review delves into the intricate and often challenging world of IM-ADRs, providing valuable insights into the complexities of immune response and the need for new strategies to predict and prevent these adverse events. It's like exploring a hidden oasis within the vast desert of drug development, revealing new paths towards understanding, diagnosis, and treatment. As we continue our exploration of this landscape, we gain a deeper appreciation for the delicate balance and intricate mechanisms that govern our immune system and the development of safer and more effective medications.

Date :
  1. Date Completed 2018-12-11
  2. Date Revised 2018-12-11
Further Info :

Pubmed ID

30166701

DOI: Digital Object Identifier

PMC6116582

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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