The Long Wait for a New Drug for Human African Trypanosomiasis.

Author: BakerCatriona H, WelburnSusan C

Paper Details 
Original Abstract of the Article :
Human African trypanosomiasis (HAT) is responsible for around 3000 reported cases each year. Treatments for HAT are expensive and problematic to administer, and available drugs are old and less than ideal, some with high levels of toxicity that result in debilitating and, in some cases, fatal side e...See full text at original site
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引用元:
https://doi.org/10.1016/j.pt.2018.08.006

データ提供:米国国立医学図書館(NLM)

The Race Against Time: A Camel's Perspective on Human African Trypanosomiasis

Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected tropical disease that affects millions of people. It's like a hidden oasis in the desert that's not easily found, but when you do, it's hard to escape its grasp. This disease is caused by the parasite Trypanosoma brucei and transmitted by the tsetse fly. This research delves into the challenges and limitations of current drug development for HAT. Despite the urgent need for effective treatment, progress has been slow, leaving patients vulnerable to debilitating side effects and even death.

A Desert of Hope: The Urgent Need for New Drugs

The lack of new drug development for HAT is a serious concern. Existing drugs are often expensive, toxic, and difficult to administer. The research highlights the complex factors that hinder drug discovery, including limited funding, challenging clinical trials, and the socioeconomic realities of affected regions. There's a pressing need to accelerate research and development efforts to address this neglected disease.

Navigating the Sands of Time: The Impact of HAT on Lives

The impact of HAT is devastating, both physically and emotionally. Patients endure painful symptoms, severe neurological complications, and a constant threat of death. The lack of effective treatment options adds to the burden of this disease, making it a cruel challenge for individuals, families, and communities. This research serves as a stark reminder of the importance of global health initiatives and the need to prioritize the development of new drugs for neglected tropical diseases.

Dr. Camel's Conclusion

Like a weary camel struggling through the desert, those affected by HAT face an arduous journey with limited resources. This research shines a light on the urgent need for a new oasis of hope—a cure for this neglected tropical disease. As researchers, we must continue to explore new avenues for drug development and advocate for increased funding and support for initiatives aimed at eradicating HAT. Together, we can work towards a future where no one is left behind in the desert of disease.
Date :
  1. Date Completed 2019-01-16
  2. Date Revised 2019-01-16
Further Info :

Pubmed ID

30181071

DOI: Digital Object Identifier

10.1016/j.pt.2018.08.006

Related Literature

SNS
PICO Info
in preparation
Languages

English

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