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Coronary artery spasms due to tyrosine kinase inhibitors used in chronic myeloid leukemia.

Author: BlijlevensN M A, CramerG E, FietsR B, StaalA H J

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report describes two patients who experienced coronary artery spasm likely due to tyrosine kinase inhibitors (TKIs) used for the treatment of chronic myeloid leukemia (CML). While TKIs are generally well-tolerated, this report highlights a potential, albeit rare, cardiovascular side effect.
Paper Details　
Original Abstract of the Article :
Tyrosine kinase inhibitors (TKIs) have changed the landscape of treatment for patients with chronic myeloid leukemia (CML) leading to a life expectancy comparable to the general population. Side effects commonly encountered during TKI treatment are pleural effusion due to use of dasatinib and vascul...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/30220658

データ提供：米国国立医学図書館（NLM）

Coronary Artery Spasms: A New Side Effect of Tyrosine Kinase Inhibitors in CML?

This research delves into the exciting world of chronic myeloid leukemia (CML) treatment. It's like a journey through a vast desert, where new discoveries are constantly being made, and the landscape is changing. The authors explore the use of tyrosine kinase inhibitors (TKIs), which are like magical oases in the CML desert, offering a lifeline to patients. They present two cases of coronary artery spasms (CAS) that seem to be linked to TKI treatment. This is a new finding, like stumbling upon a hidden oasis in the desert. This research sheds light on the potential side effects of these life-changing medications.

A Rare Oasis in the CML Desert: New Side Effects of TKIs

This research shows the incredible impact of TKIs in extending the lives of CML patients. It's like finding a hidden oasis in the vast desert of CML. However, this oasis may come with some unexpected challenges. The authors found two cases of CAS that seemed to be related to TKI treatment, which is like discovering a hidden danger in the oasis. This suggests that more research is needed to understand the full scope of the potential side effects of these medications.

The Importance of Vigilance: Navigating the CML Treatment Desert

This research highlights the importance of careful monitoring and vigilance when using TKIs. It's like being a careful traveler in a vast and sometimes unpredictable desert. By being aware of the potential side effects, we can navigate the CML treatment desert with greater safety and success. This research serves as a reminder that even the most effective medications can have unexpected consequences. It's a reminder to always be vigilant and open to new discoveries in the ever-changing landscape of medicine.

Dr.Camel's Conclusion

This study uncovers a potential new side effect of TKIs, coronary artery spasms, reminding us that even in the oasis of effective CML treatment, there may be hidden dangers. It's a reminder to be constantly vigilant and observant in the vast desert of medical research, searching for new knowledge and understanding.

Date :
  1. Date Completed 2019-10-07
  2. Date Revised 2019-10-07
Further Info :

Pubmed ID

30220658

DOI: Digital Object Identifier

30220658

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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