Current developments in pharmacotherapy for actinic keratosis.

Author: BianchiLuca, CampioneElena, Di PreteMonia, DiluvioLaura, GarofaloVirginia, MazzeoMauro, MazzilliSara, VenturaAlessandra

Paper Details 
Original Abstract of the Article :
Actinic keratosis (AK) is a superficial squamous cell carcinoma (SCC) where chronic sun exposure playing central role in its pathogenesis. UVB causes direct damage to DNA, producing pyrimidine dimers, and suppressing the protective role of p53. The stepwise progression of AK, with increased expressi...See full text at original site
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引用元:
https://doi.org/10.1080/14656566.2018.1523896

データ提供:米国国立医学図書館(NLM)

Actinic Keratosis: A Skin Condition as Devastating as a Desert Sandstorm

Actinic keratosis (AK), a precancerous skin condition, is like a persistent sandstorm that erodes and damages the skin. Exposure to the sun's harmful ultraviolet (UV) rays is the primary culprit, causing DNA damage and weakening the skin's defenses. This review explores current developments in pharmacotherapy for AK, seeking effective treatments that can mitigate the risks and restore the skin's health, much like a resourceful traveler finding shelter and relief from a raging sandstorm.

New Frontiers in AK Treatment

This review examines the pathogenesis of AK and highlights the importance of targeted treatments that address the underlying mechanisms of this condition. It discusses various pharmacotherapeutic approaches, including topical medications, photodynamic therapy, and cryotherapy, each offering unique benefits in managing AK, like a desert traveler utilizing a variety of tools and strategies to survive.

Protecting Your Skin from the Sun

This review emphasizes the importance of sun protection as a crucial strategy for preventing AK and protecting the skin's health. It's like a desert traveler seeking shade and covering themselves from the harsh sun. The review also encourages individuals to be aware of the risk factors for AK and to seek early diagnosis and treatment, ensuring a smoother journey through the desert of skin health.

Dr.Camel's Conclusion

This review provides valuable insights into the treatment of actinic keratosis, offering a roadmap for managing this precancerous skin condition. It's like a seasoned desert explorer guiding travelers through the treacherous landscape of sun damage, protecting them from the harsh elements. The review emphasizes the importance of sun protection and early detection, key steps in safeguarding skin health and preventing the development of more serious conditions.
Date :
  1. Date Completed 2018-12-11
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

30222011

DOI: Digital Object Identifier

10.1080/14656566.2018.1523896

Related Literature

SNS
PICO Info
in preparation
Languages

English

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